Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

Charge detection mass spectrometry (CDMS) is a single-particle technique where the
masses of individual ions are determined from simultaneous measurement of their mass-to …

Viruses are nanoscale entities containing a nucleic acid genome encased in a protein shell
called a capsid and in some cases are surrounded by a lipid bilayer membrane. This review …

We review approaches aimed at deciphering the physical mechanisms responsible for viral
structure and assembly. We discuss the basic principles of condensed matter physics …

Most viruses use a hollow protein shell, the capsid, to enclose the viral genome. Virus
capsids are large, symmetric oligomers made of many copies of one or a few types of protein …

Viruses play a role in a significant portion of human diseases, as well as those of other
animals, plants, and bacteria. This chapter focuses on the use of theoretical and …

Viruses are highly ordered supramolecular complexes that have evolved to propagate by
hijacking the host cell's machinery. Although viruses are very diverse, spreading through …

Understanding how virus capsids assemble around their nucleic acid (NA) genomes could
promote efforts to block viral propagation or to reengineer capsids for gene therapy …

Advances in electron cryo-microscopy have enabled structure determination of
macromolecules at near-atomic resolution. However, structure determination, even using de …

Using cross-linking coupled to matrix-assisted laser desorption/ionization mass
spectrometry and CLIP-Seq sequencing, we determined the peptide and oligonucleotide …