The role of pro-inflammatory cytokines in the neuroinflammation and neurogenesis of schizophrenia

KS Na, HY Jung, YK Kim - Progress in Neuro-Psychopharmacology and …, 2014 - Elsevier
Schizophrenia is a serious mental illness with chronic symptoms and significant impairment
in psychosocial functioning. Although novel antipsychotics have been developed, the …

Cytokine imbalance in schizophrenia. from research to clinic: potential implications for treatment

M Reale, E Costantini, NH Greig - Frontiers in psychiatry, 2021 - frontiersin.org
Cytokines are one of the most important components of the immune system. They
orchestrate the brain's response to infectious and other exogenous insults and are crucial …

Inflammatory cytokines and neurological and neurocognitive alterations in the course of schizophrenia

AM Fineberg, LM Ellman - Biological psychiatry, 2013 - Elsevier
A growing body of evidence suggests that immune alterations, especially those related to
inflammation, are associated with increased risk of schizophrenia and schizophrenia-related …

Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women

S Shifman, M Johannesson, M Bronstein… - PLoS …, 2008 - journals.plos.org
Sex differences in schizophrenia are well known, but their genetic basis has not been
identified. We performed a genome-wide association scan for schizophrenia in an …

Converging evidence for a pseudoautosomal cytokine receptor gene locus in schizophrenia

T Lencz, TV Morgan, M Athanasiou, B Dain… - Molecular …, 2007 - nature.com
Schizophrenia is a strongly heritable disorder, and identification of potential candidate
genes has accelerated in recent years. Genomewide scans have identified multiple large …

Predictive value of family history on severity of illness: the case for depression, anxiety, alcohol dependence, and drug dependence

BJ Milne, A Caspi, HL Harrington… - Archives of general …, 2009 - jamanetwork.com
Context If family history is associated with clinical features that are thought to index
seriousness of disorder, this could inform clinicians predicting patients' prognosis and …

Prenatal inflammation and neurodevelopment in schizophrenia: a review of human studies

BJ Miller, N Culpepper, MH Rapaport… - Progress in Neuro …, 2013 - Elsevier
A confluence of evidence supports an association between prenatal inflammation and risk of
schizophrenia. Outside of studies of prenatal infections and risk of schizophrenia, other …

Immune system gene dysregulation in autism and schizophrenia

M Michel, MJ Schmidt, K Mirnics - Developmental neurobiology, 2012 - Wiley Online Library
Gene* environment interactions play critical roles in the emergence of autism and
schizophrenia pathophysiology. In both disorders, recent genetic association studies have …

Schizophrenia gene networks and pathways and their applications for novel candidate gene selection

J Sun, P Jia, AH Fanous, E van den Oord, X Chen… - PloS one, 2010 - journals.plos.org
Background Schizophrenia (SZ) is a heritable, complex mental disorder. We have seen
limited success in finding causal genes for schizophrenia from numerous conventional …

IL-3 in the development and function of basophils

G Varricchi, R Poto, G Marone, JT Schroeder - Seminars in immunology, 2021 - Elsevier
The β common chain (βc) cytokine family includes granulocyte-macrophage colony-
stimulating factor (GM-CSF), interleukin-3 (IL-3) and IL-5, all of which use βc as key …