An apple a day to keep the Parkinson's disease doctor away?

BR Bloem, E Post, DA Hall - Annals of Neurology, 2023 - Wiley Online Library
It is challenging to reliably assess the motor features of Parkinson's disease in real‐time.
This has motivated the search for new digital outcomes that can objectively and remotely …

Towards a global view of Parkinson's disease genetics

M Khani, C Cerquera‐Cleves, M Kekenadze… - Annals of …, 2024 - Wiley Online Library
Parkinson's disease (PD) is a global health challenge, yet historically studies of PD have
taken place predominantly in European populations. Recent genetics research conducted in …

Parkinson's disease is predominantly a genetic disease

SY Lim, C Klein - Journal of Parkinson's Disease, 2024 - content.iospress.com
The discovery of a pathogenic variant in the alpha-synuclein (SNCA) gene in the Contursi
kindred in 1997 indisputably confirmed a genetic cause in a subset of Parkinson's disease …

Access to device-aided therapies in advanced Parkinson's disease: navigating clinician biases, patient preference, and prognostic uncertainty

M Auffret, D Weiss, F Stocchi, M Vérin… - Journal of Neural …, 2023 - Springer
Abstract Device-aided therapies (DAT), which include deep brain stimulation and pump-
based continuous dopaminergic stimulation with either levodopa or apomorphine, are …

The inhibitory effects of plant additives on biogenic amine formation in fermented foods–a review

O Świder, MŁ Roszko, M Wójcicki - Critical Reviews in Food …, 2023 - Taylor & Francis
Fermented food has unique properties and high nutritional value, and thus, should constitute
a basic element of a balanced and health-promoting diet. However, it can accumulate …

Delivering multidisciplinary rehabilitation Care in Parkinson's disease: an international consensus statement

JG Goldman, D Volpe, TD Ellis… - Journal of …, 2024 - content.iospress.com
Background: Parkinson's disease (PD) is a complex neurodegenerative disorder impacting
everyday function and quality of life. Rehabilitation plays a crucial role in improving …

Transforming drug development for neurological disorders: proceedings from a multidisease area workshop

D Stephenson, R Belfiore-Oshan, Y Karten, J Keavney… - …, 2023 - Elsevier
Neurological disorders represent some of the most challenging therapeutic areas for
successful drug approvals. The escalating global burden of death and disability for such …

The lived experience of stigma and parkinson's disease in Kenya: a public health challenge

N Fothergill-Misbah - BMC Public Health, 2023 - Springer
Background As a disease characterised by non-motor and very visible motor symptoms,
Parkinson's disease has been associated with multiple forms of stigma, while awareness …

Exploring the levodopa-paradox of freezing of gait in dopaminergic medication-naïve Parkinson's disease populations

JAF Jansen, TTC Capato, SKL Darweesh… - npj Parkinson's …, 2023 - nature.com
The relationship between dopaminergic treatment and freezing of gait (FOG) in Parkinson's
disease (PD) is complex: levodopa is the most effective symptomatic treatment for FOG, but …

Prevalence and Incidence of Parkinson's Disease in Latin America: A Meta‐Analysis

DJ Kim, AL Isidro‐Pérez, M Doering… - Movement …, 2024 - Wiley Online Library
Background Parkinson's disease (PD) is a rapidly growing neurodegenerative disorder, but
up‐to‐date epidemiological data are lacking in Latin America. We sought to estimate the …