The first matrix metalloproteinase (MMP) was discovered in 1962 from the tail of a tadpole by
its ability to degrade collagen. As their name suggests, matrix metalloproteinases are …

Simple Summary MMP9, due to its proteolytic activity, plays a key role in tumorigenesis by
regulating migration, epithelial-to-mesenchymal transition and survival of cancer cells …

Background Inflammation in the lung is the body's natural response to injury. It acts to
remove harmful stimuli such as pathogens, irritants, and damaged cells and initiate the …

Matrix metalloproteinase (MMP)-9, one of the most widely investigated MMPs, regulates
pathological remodeling processes that involve inflammation and fibrosis in cardiovascular …

Research on matrix metalloproteinases (MMPs) and in particular on gelatinase B, alias MMP-
9, has grown exponentially in the decade 2003–2012. Structural details about flexibility of …

Abstract Background Matrix metalloproteinases (MMPs) are a family of ubiquitously
expressed zinc-dependent endopeptidases with broad substrate specificity and strictly …

Periodontitis is a chronic inflammatory condition of the periodontium involving interactions
between bacterial products, numerous cell populations and inflammatory mediators. It is …

Matrix metalloproteinases (MMPs) were discovered because of their role in amphibian
metamorphosis, yet they have attracted more attention because of their roles in disease …

As their name implies, matrix metalloproteinases are thought to be responsible for the
turnover and degradation of the extracellular matrix. However, matrix degradation is neither …

The biological roles of the matrix metalloproteinases (MMPs) have been traditionally
associated with the degradation and turnover of most of the components of the extracellular …