The Hippo signalling pathway has emerged as a major player in many aspects of liver
biology, such as development, cell fate determination, homeostatic function and …

Two decades of studies in multiple model organisms have established the Hippo pathway
as a key regulator of organ size and tissue homeostasis. By inhibiting YAP and TAZ …

Emerging studies have suggested that the Hippo pathway is involved in the tumorigenesis of
hepatocellular carcinoma (HCC). However, the key regulator of the Hippo pathway in liver …

ABSTRACT YAP and TAZ proteins are transcriptional coactivators encoded by paralogous
genes, which shuttle between the cytoplasm and the nucleus in response to multiple inputs …

The transcriptional regulators YAP and TAZ are the focus of intense interest given their
remarkable biological properties in development, tissue homeostasis and cancer. YAP and …

The joint pollution of microplastics (MPs) and di-(2-ethylhexyl) phthalic acid (DEHP) often
occurs, and consequently poses a serious threat to human and animal health, which has …

The Hippo signalling pathway is an emerging growth control and tumour suppressor
pathway that regulates cell proliferation and stem cell functions. Defects in Hippo signalling …

Tissue repair and regenerative medicine address the important medical needs to replace
damaged tissue with functional tissue. Most regenerative medicine strategies have focused …

Telomerase (TERT) activation is a fundamental step in tumorigenesis. By maintaining
telomere length, telomerase relieves a main barrier on cellular lifespan, enabling limitless …

The Hippo signaling pathway, also known as the Salvador− Warts− Hippo pathway, is a
regulator of organ size. The pathway takes its name from the Drosophila protein kinase …