The yin and yang effect of the apelinergic system in oxidative stress

B Fibbi, G Marroncini, L Naldi, A Peri - International Journal of Molecular …, 2023 - mdpi.com
Apelin is an endogenous ligand for the G protein-coupled receptor APJ and has multiple
biological activities in human tissues and organs, including the heart, blood vessels …

Mitigation of cisplatin-induced nephrotoxicity by chelidonic acid in Wistar rats

SI Khairnar, YA Kulkarni, K Singh - Journal of Trace Elements in Medicine …, 2024 - Elsevier
Introduction Cisplatin, an anti-cancer drug is used to treat a wide range of solid tumors.
Nevertheless, nephrotoxicity is the major adverse effect that restricts its clinical application …

The impact of apelin-13 on cisplatin-induced endocrine pancreas damage in rats: an in vivo study

S Ciftel, L Tumkaya, S Saral, T Mercantepe… - Histochemistry and cell …, 2024 - Springer
Apelin-13 is a peptide hormone that regulates pancreatic endocrine functions, and its
benefits on the endocrine pancreas are of interest. This study aims to investigate the …

[HTML][HTML] Anthrahydroquinone-2, 6-disulfonate alleviates paraquat-induced kidney injury via the apelin-APJ pathway in rats

Q Li, B Wang, KW Lin, T Deng, QF Huang… - Asian Pacific Journal …, 2022 - journals.lww.com
Objective: To explore the protective effects of anthrahydroquinone-2, 6-disulfonate (AH 2
QDS) on the kidneys of paraquat (PQ) poisoned rats via the apelin-APJ pathway. Methods …

Protective Effect of Apelin-13 on D-Glutamic Acid-Induced Excitotoxicity in SH-SY5Y Cell Line: An In-Vitro Study

KY Oruç, A Oruç, G Ağtürk, K Yanar, HO Seymen - 2024 - researchsquare.com
Excitotoxicity, resulting from excessive accumulation of glutamate in the extracellular space,
leads to neuronal cell death. This study investigates the protective effects of Apelin-13 on D …