Mucoadhesive carriers for oral drug delivery
Among the various dosage forms, oral medicine has extensive benefits including ease of
administration and patients' compliance, over injectable, suppositories, ocular and nasal …
administration and patients' compliance, over injectable, suppositories, ocular and nasal …
Advances in the colon-targeted chitosan based multiunit drug delivery systems for the treatment of inflammatory bowel disease
N Kulkarni, P Jain, A Shindikar, P Suryawanshi… - Carbohydrate …, 2022 - Elsevier
Chitosan is the polymer of choice for delivery of the active moieties to the colon due to its
cationic nature that enables strong mucosal attachment. Chitosan is explored for …
cationic nature that enables strong mucosal attachment. Chitosan is explored for …
[HTML][HTML] The influence of the gut microbiota on the bioavailability of oral drugs
X Zhang, Y Han, W Huang, M Jin, Z Gao - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Due to its safety, convenience, low cost and good compliance, oral administration attracts
lots of attention. However, the efficacy of many oral drugs is limited to their unsatisfactory …
lots of attention. However, the efficacy of many oral drugs is limited to their unsatisfactory …
Hydrothermal synthesis of ZnCr-LDH/tungsten carbide composite: a disposable electrochemical strip for mesalazine analysis
The development of novel electrocatalyst materials with excellent characteristics is inevitably
needed to satisfy the practical application of electrochemical sensors. In this study, the 2D …
needed to satisfy the practical application of electrochemical sensors. In this study, the 2D …
Advances in the treatment of inflammatory bowel disease: Focus on polysaccharide nanoparticulate drug delivery systems
H Hadji, K Bouchemal - Advanced Drug Delivery Reviews, 2022 - Elsevier
The complex pathogenesis of inflammatory bowel disease (IBD) explains the several
hurdles for finding an efficient approach to cure it. Nowadays, therapeutic protocols aim to …
hurdles for finding an efficient approach to cure it. Nowadays, therapeutic protocols aim to …
Recent advances on formation mechanism and functionality of chitosan-based conjugates and their application in o/w emulsion systems: A review
Q Zhao, L Fan, Y Liu, J Li - Food chemistry, 2022 - Elsevier
Chitosan is very attractive in the food industry due to its good biocompatibility and high
biodegradability. In particular, it can be used as a preferred material for the fabrication of …
biodegradability. In particular, it can be used as a preferred material for the fabrication of …
Big family of nano-and microscale drug delivery systems ranging from inorganic materials to polymeric and stimuli-responsive carriers as well as drug-conjugates
Z Shariatinia - Journal of Drug Delivery Science and Technology, 2021 - Elsevier
Traditional drug administration routs suffer from low selective distribution, poor solubility, fast
elimination and damaging adjacent healthy tissues (especially in cancer therapy). Thus …
elimination and damaging adjacent healthy tissues (especially in cancer therapy). Thus …
Mesalazine and inflammatory bowel disease–From well-established therapies to progress beyond the state of the art
Inflammatory bowel disease incidence has been constantly rising for the past few decades.
Current therapies attempt to mitigate its symptoms since no cure is established. The most …
Current therapies attempt to mitigate its symptoms since no cure is established. The most …
Molecular modifications, biological activities, and applications of chitosan and derivatives: A recent update
R Lima, C Fernandes, MMM Pinto - Chirality, 2022 - Wiley Online Library
Polysaccharides arouse great interest due to their structure and unique properties, such as
biocompatibility, biodegradability, and absence of toxicity. Polysaccharides from marine …
biocompatibility, biodegradability, and absence of toxicity. Polysaccharides from marine …
Eudragit s100 coated iron oxide-chitosan nanocomposites for colon targeting of 5-aminosalicylic acid ameliorate ulcerative colitis by improving intestinal barrier …
D Zhang, H Wan, R Zhao, Y Zhang, H Chen - International …, 2024 - Elsevier
The therapeutic effect of 5-amino salicylic acid (5-ASA), a first-line therapeutic agent for the
treatment of ulcerative colitis (UC), is limited by the modest bioavailability afforded by its oral …
treatment of ulcerative colitis (UC), is limited by the modest bioavailability afforded by its oral …