Mucoadhesive carriers for oral drug delivery

R Kumar, T Islam, M Nurunnabi - Journal of Controlled Release, 2022 - Elsevier
Among the various dosage forms, oral medicine has extensive benefits including ease of
administration and patients' compliance, over injectable, suppositories, ocular and nasal …

Advances in the colon-targeted chitosan based multiunit drug delivery systems for the treatment of inflammatory bowel disease

N Kulkarni, P Jain, A Shindikar, P Suryawanshi… - Carbohydrate …, 2022 - Elsevier
Chitosan is the polymer of choice for delivery of the active moieties to the colon due to its
cationic nature that enables strong mucosal attachment. Chitosan is explored for …

[HTML][HTML] The influence of the gut microbiota on the bioavailability of oral drugs

X Zhang, Y Han, W Huang, M Jin, Z Gao - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Due to its safety, convenience, low cost and good compliance, oral administration attracts
lots of attention. However, the efficacy of many oral drugs is limited to their unsatisfactory …

Hydrothermal synthesis of ZnCr-LDH/tungsten carbide composite: a disposable electrochemical strip for mesalazine analysis

T Kokulnathan, TJ Wang, F Ahmed… - Chemical Engineering …, 2023 - Elsevier
The development of novel electrocatalyst materials with excellent characteristics is inevitably
needed to satisfy the practical application of electrochemical sensors. In this study, the 2D …

Advances in the treatment of inflammatory bowel disease: Focus on polysaccharide nanoparticulate drug delivery systems

H Hadji, K Bouchemal - Advanced Drug Delivery Reviews, 2022 - Elsevier
The complex pathogenesis of inflammatory bowel disease (IBD) explains the several
hurdles for finding an efficient approach to cure it. Nowadays, therapeutic protocols aim to …

Recent advances on formation mechanism and functionality of chitosan-based conjugates and their application in o/w emulsion systems: A review

Q Zhao, L Fan, Y Liu, J Li - Food chemistry, 2022 - Elsevier
Chitosan is very attractive in the food industry due to its good biocompatibility and high
biodegradability. In particular, it can be used as a preferred material for the fabrication of …

Big family of nano-and microscale drug delivery systems ranging from inorganic materials to polymeric and stimuli-responsive carriers as well as drug-conjugates

Z Shariatinia - Journal of Drug Delivery Science and Technology, 2021 - Elsevier
Traditional drug administration routs suffer from low selective distribution, poor solubility, fast
elimination and damaging adjacent healthy tissues (especially in cancer therapy). Thus …

Mesalazine and inflammatory bowel disease–From well-established therapies to progress beyond the state of the art

PM Veloso, R Machado, C Nobre - European Journal of Pharmaceutics and …, 2021 - Elsevier
Inflammatory bowel disease incidence has been constantly rising for the past few decades.
Current therapies attempt to mitigate its symptoms since no cure is established. The most …

Molecular modifications, biological activities, and applications of chitosan and derivatives: A recent update

R Lima, C Fernandes, MMM Pinto - Chirality, 2022 - Wiley Online Library
Polysaccharides arouse great interest due to their structure and unique properties, such as
biocompatibility, biodegradability, and absence of toxicity. Polysaccharides from marine …

Eudragit s100 coated iron oxide-chitosan nanocomposites for colon targeting of 5-aminosalicylic acid ameliorate ulcerative colitis by improving intestinal barrier …

D Zhang, H Wan, R Zhao, Y Zhang, H Chen - International …, 2024 - Elsevier
The therapeutic effect of 5-amino salicylic acid (5-ASA), a first-line therapeutic agent for the
treatment of ulcerative colitis (UC), is limited by the modest bioavailability afforded by its oral …