Studying human respiratory disease in animals–role of induced and naturally occurring models
K Williams, J Roman - The Journal of pathology, 2016 - Wiley Online Library
Respiratory disorders like asthma, emphysema, and pulmonary fibrosis affect millions of
Americans and many more worldwide. Despite advancements in medical research that have …
Americans and many more worldwide. Despite advancements in medical research that have …
The potential role of IL-33/ST2 signaling in fibrotic diseases
IL-33, a new member of the IL-1F, is widely expressed throughout the body and can be up-
regulated by stimulation with proinflammatory factors. It has been identified as a functional …
regulated by stimulation with proinflammatory factors. It has been identified as a functional …
Bryodulcosigenin attenuates bleomycin‐induced pulmonary fibrosis via inhibiting AMPK‐mediated mesenchymal epithelial transition and oxidative stress
Y Ding, L Wang, B Liu, G Ren, R Okubo… - Phytotherapy …, 2022 - Wiley Online Library
Fibrosis is a pathological result of a dysfunctional repair response to tissue injury and occurs
in several organs, including the lungs. Bryodulcosigenin (BDG) is a cucurbitane‐type …
in several organs, including the lungs. Bryodulcosigenin (BDG) is a cucurbitane‐type …
LncRNA CTD-2528L19. 6 prevents the progression of IPF by alleviating fibroblast activation
T Chen, Y Guo, J Wang, L Ai, L Ma, W He, Z Li… - Cell Death & …, 2021 - nature.com
Long non-coding RNAs (lncRNAs) have emerged as critical factors for regulating multiple
biological processes during organ fibrosis. However, the mechanism of lncRNAs in …
biological processes during organ fibrosis. However, the mechanism of lncRNAs in …
Unsupervised gene expression analyses identify IPF-severity correlated signatures, associated genes and biomarkers
Abstract Background Idiopathic Pulmonary Fibrosis (IPF) is a fatal fibrotic lung disease
occurring predominantly in middle-aged and older adults. The traditional diagnostic …
occurring predominantly in middle-aged and older adults. The traditional diagnostic …
Idiopathic pulmonary fibrosis in West Highland white terriers: An update
C Clercx, A Fastrès, E Roels - The Veterinary Journal, 2018 - Elsevier
Canine idiopathic pulmonary fibrosis (CIPF) affects middle-aged to older dogs of a single
breed, mainly the West Highland white terrier (WHWT), which is suggestive of a genetic …
breed, mainly the West Highland white terrier (WHWT), which is suggestive of a genetic …
Further characterization of computed tomographic and clinical features for staging and prognosis of idiopathic pulmonary fibrosis in West Highland white terriers
F Thierry, I Handel, G Hammond… - Veterinary radiology …, 2017 - Wiley Online Library
Idiopathic pulmonary fibrosis is an interstitial lung disease of unknown etiology resulting in
progressive interstitial fibrosis, with a known predilection in West Highland white terriers. In …
progressive interstitial fibrosis, with a known predilection in West Highland white terriers. In …
Protective effect of ginsenoside Rg1 on bleomycin-induced pulmonary fibrosis in rats: involvement of caveolin-1 and TGF-β1 signal pathway
H Zhan, F Huang, W Ma, Z Zhao, H Zhang… - Biological and …, 2016 - jstage.jst.go.jp
Idiopathic pulmonary fibrosis (IPF) is a progressive disease with poor prognosis and high
mortality rate. Panax Notoginseng Saponins (PNS), extracted from Panax Notoginseng as a …
mortality rate. Panax Notoginseng Saponins (PNS), extracted from Panax Notoginseng as a …
Yangyin Yiqi Mixture Ameliorates Bleomycin‐Induced Pulmonary Fibrosis in Rats through Inhibiting TGF‐β1/Smad Pathway and Epithelial to Mesenchymal Transition
L Meng, X Zhang, H Wang, H Dong… - Evidence‐Based …, 2019 - Wiley Online Library
Objective. The aim of the current study was to investigate the protective effect of Yangyin Yiqi
Mixture (YYYQ) on Bleomycin‐induced pulmonary fibrosis in rats based on TGF‐β1/Smad …
Mixture (YYYQ) on Bleomycin‐induced pulmonary fibrosis in rats based on TGF‐β1/Smad …
Matrix metalloproteinase‐2,‐7, and‐9 activities in dogs with idiopathic pulmonary fibrosis compared to healthy dogs and dogs with other respiratory diseases
M Määttä, HP Laurila, S Holopainen… - Journal of Veterinary …, 2021 - Wiley Online Library
Background Canine idiopathic pulmonary fibrosis (CIPF) is a chronic, interstitial lung
disease that mainly affects West Highland white terriers (WHWTs) and is characterized by …
disease that mainly affects West Highland white terriers (WHWTs) and is characterized by …