Inorganic nano-drug delivery systems for crossing the blood–brain barrier: Advances and challenges

Q Tan, S Zhao, T Xu, Q Wang, M Zhang, L Yan… - Coordination Chemistry …, 2023 - Elsevier
The blood–brain barrier (BBB) exists between plasma and brain tissue. It comprises a
capillary wall and glial cells and prevents external substances, including therapeutic agents …

Functionalized nanomaterials capable of crossing the blood–brain barrier

S Zha, H Liu, H Li, H Li, KL Wong, AH All - ACS nano, 2024 - ACS Publications
The blood–brain barrier (BBB) is a specialized semipermeable structure that highly
regulates exchanges between the central nervous system parenchyma and blood vessels …

[HTML][HTML] Early diagnosis of lung cancer using magnetic nanoparticles-integrated systems

A Rastogi, K Yadav, A Mishra, MS Singh… - Nanotechnology …, 2022 - degruyter.com
Lung cancer (LC) has high morbidity and fatality rate that can be attributed to its poor
diagnostic and monitoring facilities. Hence, there is a need to design advanced detection …

[HTML][HTML] Understanding Glioblastoma Signaling, Heterogeneity, Invasiveness, and Drug Delivery Barriers

N Rabah, FE Ait Mohand… - International Journal of …, 2023 - mdpi.com
The most prevalent and aggressive type of brain cancer, namely, glioblastoma (GBM), is
characterized by intra-and inter-tumor heterogeneity and strong spreading capacity, which …

Numerical studies on magnetic driven targeted drug delivery in human vasculature

NK Tamboli, JS Murallidharan - Journal of the Indian Institute of Science, 2024 - Springer
Magnetic driven targeted drug delivery (TDD) involves the manipulation of magnetic drug
carriers, such as nano/micro particles or bubbles, within the body using external magnetic …

[HTML][HTML] Biogenic and biomimetic functionalized magnetic nanosystem: Synthesis, properties, and biomedical applications

S Nadaf, GK Jena, N Rarokar, N Gurav, M Ayyanar… - Hybrid Advances, 2023 - Elsevier
Biogenic and biomimetic nanosystems (BBS) are the advanced hybrid nanomaterial used
for treatment and diagnosis. These nanosystems' true bench-to-bedside potential makes …

[HTML][HTML] Passing of Nanocarriers across the Histohematic Barriers: Current Approaches for Tumor Theranostics

K Gareev, R Tagaeva, D Bobkov, N Yudintceva… - Nanomaterials, 2023 - mdpi.com
Over the past several decades, nanocarriers have demonstrated diagnostic and therapeutic
(ie, theranostic) potencies in translational oncology, and some agents have been further …

[HTML][HTML] New insights into Alzheimer's disease: Novel pathogenesis, drug target and delivery

H Chen, J Xu, H Xu, T Luo, Y Li, K Jiang, Y Shentu… - Pharmaceutics, 2023 - mdpi.com
Alzheimer's disease (AD), the most common type of dementia, is characterized by senile
plaques composed of amyloid β protein (Aβ) and neurofilament tangles derived from the …

[HTML][HTML] Hopping the Hurdle: Strategies to Enhance the Molecular Delivery to the Brain through the Blood–Brain Barrier

SA Cogill, JH Lee, MT Jeon, DG Kim, Y Chang - Cells, 2024 - mdpi.com
Modern medicine has allowed for many advances in neurological and neurodegenerative
disease (ND). However, the number of patients suffering from brain diseases is ever …

Magnetic hybrid nanovesicles for the precise diagnosis and treatment of central nervous system disorders

S Salatin, M Farhoudi, S Sadigh-Eteghad… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Central nervous system (CNS)-related disorders are increasingly being
recognized as a global health challenge worldwide. There are significant challenges for …