The neural basis of psychedelic action

AC Kwan, DE Olson, KH Preller, BL Roth - Nature Neuroscience, 2022 - nature.com
Psychedelics are serotonin 2A receptor agonists that can lead to profound changes in
perception, cognition and mood. In this review, we focus on the basic neurobiology …

Psychedelic drugs: neurobiology and potential for treatment of psychiatric disorders

FX Vollenweider, KH Preller - Nature Reviews Neuroscience, 2020 - nature.com
Renewed interest in the use of psychedelics in the treatment of psychiatric disorders
warrants a better understanding of the neurobiological mechanisms underlying the effects of …

[HTML][HTML] Pharmacological, neural, and psychological mechanisms underlying psychedelics: A critical review

M van Elk, DB Yaden - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …

[HTML][HTML] REBUS and the anarchic brain: toward a unified model of the brain action of psychedelics

RL Carhart-Harris, KJ Friston - Pharmacological reviews, 2019 - ASPET
This paper formulates the action of psychedelics by integrating the free-energy principle and
entropic brain hypothesis. We call this formulation relaxed beliefs under psychedelics …

Models of psychedelic drug action: modulation of cortical-subcortical circuits

MK Doss, MB Madden, A Gaddis, MB Nebel… - Brain, 2022 - academic.oup.com
Classic psychedelic drugs such as psilocybin and lysergic acid diethylamide (LSD) have
recaptured the imagination of both science and popular culture, and may have efficacy in …

Hallucinogens in mental health: preclinical and clinical studies on LSD, psilocybin, MDMA, and ketamine

D De Gregorio, A Aguilar-Valles, KH Preller… - Journal of …, 2021 - Soc Neuroscience
A revamped interest in the study of hallucinogens has recently emerged, especially with
regard to their potential application in the treatment of psychiatric disorders. In the last …

Psychedelic psychiatry's brave new world

D Nutt, D Erritzoe, R Carhart-Harris - Cell, 2020 - cell.com
After a legally mandated, decades-long global arrest of research on psychedelic drugs,
investigation of psychedelics in the context of psychiatric disorders is yielding exciting …

Psychedelics

DE Nichols - Pharmacological reviews, 2016 - ASPET
Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter
perception and mood and affect numerous cognitive processes. They are generally …

A neurophenomenological approach to non-ordinary states of consciousness: hypnosis, meditation, and psychedelics

C Timmermann, PR Bauer, O Gosseries… - Trends in cognitive …, 2023 - cell.com
No contemporary unifying framework has been provided for the study of non-ordinary states
of consciousness (NSCs) despite increased interest in hypnosis, meditation, and …

Effective connectivity changes in LSD-induced altered states of consciousness in humans

KH Preller, A Razi, P Zeidman… - Proceedings of the …, 2019 - National Acad Sciences
Psychedelics exert unique effects on human consciousness. The thalamic filter model
suggests that core effects of psychedelics may result from gating deficits, based on a …