Osteochondral (OC) repair is an extremely challenging topic due to the complex biphasic
structure and poor intrinsic regenerative capability of natural osteochondral tissue. In …

Secretomes of mesenchymal stem cells (MSCs) have been successfully studied in
preclinical models for several biomedical applications, including tissue engineering, drug …

Scaffold-free techniques in the developmental tissue engineering area are designed to
mimic in vivo embryonic processes with the aim of biofabricating, in vitro, tissues with more …

Current regenerative cartilage therapies are associated with several drawbacks such as
dedifferentiation of chondrocytes during expansion and the formation of fibrocartilage …

Three-dimensional (3D) bioprinting, a promising advancement in tissue engineering
technology, involves the robotic, layer-by-layer additive biofabrication of functional 3D tissue …

Abstract The new coronavirus (2019‐nCoV) or the severe acute respiratory syndrome
coronavirus 2 (SARS‐CoV‐2) was officially declared by the World Health Organization …

Articular cartilage lesions are prevalent and affect one out of seven American adults and
many young patients. Cartilage is not capable of regeneration on its own. Existing …

Osteoarthritis (OA) is a severely painful and debilitating disease of the joint, which brings
about degradation of the articular cartilage and currently has few therapeutic solutions. Two …

In recent years, the incidence of osteoarthritis (OA) has been increasing worldwide. This
disease not only affects the articular cartilage but also impairs the subchondral bone and …

Background: Bone marrow stimulation (BMS) is the most used operative treatment in
repairing cartilage defect clinically, but always results in fibrocartilage formation, which is …