Chrysin: Pharmacological and therapeutic properties

S Naz, M Imran, A Rauf, IE Orhan, MA Shariati… - Life sciences, 2019 - Elsevier
Chrysin is a promising phytochemical that is categorized under the class of flavonoids based
on its chemical structure. Naturally, it is widely present in propolis, honey, passion fruit, and …

Neuroprotective potential of chrysin: Mechanistic insights and therapeutic potential for neurological disorders

A Mishra, PS Mishra, R Bandopadhyay, N Khurana… - Molecules, 2021 - mdpi.com
Chrysin, a herbal bioactive molecule, exerts a plethora of pharmacological effects, including
anti-oxidant, anti-inflammatory, neuroprotective, and anti-cancer. A growing body of …

Effect of antidepressant medications on semen parameters and male fertility

LA Beeder, MK Samplaski - International Journal of Urology, 2020 - Wiley Online Library
Antidepressant medications are commonly used in males of reproductive age for long‐term
treatment of depression, as well as other disorders. Although antidepressants are known to …

Interplay between male reproductive system dysfunction and the therapeutic effect of flavonoids

RJ Ye, JM Yang, DM Hai, N Liu, L Ma, XB Lan, JG Niu… - Fitoterapia, 2020 - Elsevier
Male infertility has affected many families around the world. However, due to the mechanism
underlying male reproductive system dysfunction are not completely elucidated, the use of …

The flavonoid chrysin protects against testicular apoptosis induced by torsion/detorsion in adult rats

ARR Abadi, LM Boukani, M Shokoohi, N Vaezi… - Andrologia, 2023 - Wiley Online Library
In the present work, we examined the beneficial efficacy of chrysin as a natural flavonoid on
testicular torsion/detorsion damages among adult male rats. Forty‐eight male Wistar rats …

The protective effects of baicalin and chrysin against emamectin benzoate-induced toxicity in Wistar albino rats

MY Tekeli, G Eraslan, LÇ Bayram, C Aslan… - … Science and Pollution …, 2023 - Springer
The aim of this study was to investigate the effects of baicalin, chrysin and their combinations
against emamectin benzoate-induced toxicity in rats. For this purpose, sixty four rats were …

Pharmacological update of mirtazapine: a narrative literature review

EHM Hassanein, HS Althagafy, MA Baraka… - Naunyn-schmiedeberg's …, 2024 - Springer
Mirtazapine (MTZ) is an antidepressant drug with an exceptional pharmacological profile. It
also has an excellent safety and tolerability profile. The present review provides a …

[HTML][HTML] pH-sensitive in situ gel of mirtazapine Invasomes for rectal drug delivery: Protruded bioavailability and anti-depressant efficacy

EM Eissa, AM El Sisi, MA Bekhet, FIA El-Ela… - Pharmaceuticals, 2024 - mdpi.com
The present research emphasizes fabrication alongside the assessment of an innovative
nano-vesicular membranous system known as invasomes (NVMs) laden with Mirtazapine …

Optimization of mirtazapine loaded into mesoporous silica nanostructures via Box-Behnken design: in-vitro characterization and in-vivo assessment

AA Musallam, MA Mahdy, HM Elnahas, RA Aldeeb - Drug Delivery, 2022 - Taylor & Francis
Employment of mesoporous silica nanostructures (MSNs) in the drug delivery field has
shown a significant potential for improving the oral delivery of active pharmaceutical …

Protective role of chrysin on doxorubicin‐induced oxidative stress and DNA damage in rat testes

S Belhan, M Özkaraca, U Özdek, AU Kömüroğlu - Andrologia, 2020 - Wiley Online Library
This study investigated the role of chrysin (CR) in DNA damage likely to occur in the testicle
and oxidative stress caused by doxorubicin (DXR). Twenty‐eight rats were divided into four …