The polinton-like supergroup of viruses: evolution, molecular biology, and taxonomy

EV Koonin, MG Fischer, JH Kuhn… - … and Molecular Biology …, 2024 - journals.asm.org
SUMMARY Polintons are 15–20 kb-long self-synthesizing transposons that are widespread
in eukaryotic, and in particular protist, genomes. Apart from a transposase and a protein …

DNA polymerases for whole genome amplification: considerations and future directions

CD Ordóñez, M Redrejo-Rodríguez - International Journal of Molecular …, 2023 - mdpi.com
In the same way that specialized DNA polymerases (DNAPs) replicate cellular and viral
genomes, only a handful of dedicated proteins from various natural origins as well as …

Plant organellar DNA polymerases are replicative and translesion DNA synthesis polymerases

N Baruch-Torres, LG Brieba - Nucleic acids research, 2017 - academic.oup.com
Genomes acquire lesions that can block the replication fork and some lesions must be
bypassed to allow survival. The nuclear genome of flowering plants encodes two family-A …

Identification of a unique insertion in plant organellar DNA polymerases responsible for 5′-dRP lyase and strand-displacement activities: Implications for Base …

CH Trasviña-Arenas, N Baruch-Torres… - DNA repair, 2018 - Elsevier
Plant mitochondrial and chloroplast genomes encode essential proteins for oxidative
phosphorylation and photosynthesis. For proper cellular function, plant organelles must …

Horizontal transfer of β-carbonic anhydrase genes from prokaryotes to protozoans, insects, and nematodes

R Zolfaghari Emameh, HR Barker, MEE Tolvanen… - Parasites & vectors, 2016 - Springer
Background Horizontal gene transfer (HGT) is a movement of genetic information occurring
outside of normal mating activities. It is especially common between prokaryotic …

Episomal and chromosomal DNA replication and recombination in Entamoeba histolytica

S Bhattacharya - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Entamoeba histolytica is the causative agent of amoebiasis. DNA replication studies in E.
histolytica first started with the ribosomal RNA genes located on episomal circles. Unlike …

DNA polymerase from temperate phage Bam35 is endowed with processive polymerization and abasic sites translesion synthesis capacity

M Berjón-Otero, L Villar, M de Vega… - Proceedings of the …, 2015 - National Acad Sciences
DNA polymerases (DNAPs) responsible for genome replication are highly faithful enzymes
that nonetheless cannot deal with damaged DNA. In contrast, translesion synthesis (TLS) …

Evolution of Base Excision Repair in Entamoeba histolytica is shaped by gene loss, gene duplication, and lateral gene transfer

CH Trasviña-Arenas, SS David, L Delaye… - DNA repair, 2019 - Elsevier
During its life cycle, the protist parasite Entamoeba histolytica encounters reactive oxygen
and nitrogen species that alter its genome. Base excision repair (BER) is one of the most …

Dispensability of the [4Fe‐4S] cluster in novel homologues of adenine glycosylase MutY

CH Trasviña‐Arenas, LM Lopez‐Castillo… - The FEBS …, 2016 - Wiley Online Library
7, 8‐Dihydro‐8‐deoxyguanine (8oG) is one of the most common oxidative lesions in DNA.
DNA polymerases misincorporate an adenine across from this lesion. Thus, 8oG is a highly …

Fusion of a superfamily 1 helicase and an inactivated DNA polymerase is a signature of common evolutionary history of Polintons, polinton-like viruses, Tlr1 …

M Krupovic, N Yutin, EV Koonin - Virus Evolution, 2016 - academic.oup.com
Abstract Polintons (polintoviruses), polinton-like viruses (PLVs) and virophages belong to a
recently described major class of eukaryotic viruses that is characterized by a distinct virion …