Calcium phosphate nanoparticles-based systems for siRNA delivery
X Xu, Z Li, X Zhao, L Keen, X Kong - Regenerative Biomaterials, 2016 - academic.oup.com
Despite the enormous therapeutic potential of siRNA as a treatment strategy, the delivery is
still a problem due to unfavorable biodistribution profiles and poor intracellular …
still a problem due to unfavorable biodistribution profiles and poor intracellular …
Aqueous-phase synthesis of iron oxide nanoparticles and composites for cancer diagnosis and therapy
The design and development of multifunctional nanoplatforms for biomedical applications
still remains to be challenging. This review reports the recent advances in aqueous-phase …
still remains to be challenging. This review reports the recent advances in aqueous-phase …
Efficient Delivery of Therapeutic siRNA by Fe3O4 Magnetic Nanoparticles into Oral Cancer Cells
L Jin, Q Wang, J Chen, Z Wang, H Xin, D Zhang - Pharmaceutics, 2019 - mdpi.com
The incidence of oral cancer is increasing due to smoking, drinking, and human
papillomavirus (HPV) infection, while the current treatments are not satisfactory. Small …
papillomavirus (HPV) infection, while the current treatments are not satisfactory. Small …
Cancer-targeted fucoidan‑iron oxide nanoparticles for synergistic chemotherapy/chemodynamic theranostics through amplification of P-selectin and oxidative stress
A combination of chemotherapy and chemodynamic therapy (CDT) is being developed to
improve the theranostic efficacy and biological safety of current therapies. However, most …
improve the theranostic efficacy and biological safety of current therapies. However, most …
[HTML][HTML] Anticancer polypyrrole-polyethylenimine drug-free nanozyme for precise B-cell lymphoma therapy
TT Nguyen, EY Chuang, YP Chen, PC Tseng… - Biomedicine & …, 2023 - Elsevier
As an alternative strategy for cancer treatment, the combination of cancer nanomedicine and
immunotherapy is promising with regard to efficacy and safety; however, precise modulation …
immunotherapy is promising with regard to efficacy and safety; however, precise modulation …
PEI-Coated Fe3O4 Nanoparticles Enable Efficient Delivery of Therapeutic siRNA Targeting REST into Glioblastoma Cells
R Wang, V Degirmenci, H Xin, Y Li, L Wang… - International journal of …, 2018 - mdpi.com
Glioblastomas (GBM) are the most frequent brain tumors lacking efficient treatment. The
increasingly elucidated gene targets make siRNA-based gene therapy a promising …
increasingly elucidated gene targets make siRNA-based gene therapy a promising …
Human 3D cultures as models for evaluating magnetic nanoparticle CNS cytotoxicity after short-and repeated long-term exposure
U De Simone, M Roccio, L Gribaldo, A Spinillo… - International journal of …, 2018 - mdpi.com
Since nanoparticles (NPs) can translocate to the brain and impact the highly vulnerable
central nervous system (CNS), novel in vitro tools for the assessment of NP-induced …
central nervous system (CNS), novel in vitro tools for the assessment of NP-induced …
Iron oxide nanoparticles with different polymer coatings for photothermal therapy
J Yang, L Fan, Y Xu, J Xia - Journal of Nanoparticle Research, 2017 - Springer
Iron oxide nanoparticles (Fe 3 O 4 NPs) have attracted significant attention in view of their
potential applications in biomedicine. Surface coatings or modifications are generally …
potential applications in biomedicine. Surface coatings or modifications are generally …
Multifunctional nanocarriers for delivering siRNA and miRNA in glioblastoma therapy: advances in nanobiotechnology-based cancer therapy
Glioblastoma multiforme (GBM) is one of the most lethal cancer due to poor diagnosis and
rapid resistance developed towards the drug. Genes associated to cancer-related …
rapid resistance developed towards the drug. Genes associated to cancer-related …
Cysteamine functionalized gold nanoparticles exhibit high efficiency delivery of genetic materials in embryonic stem cells majorly via clathrin mediated endocytosis
F Fernandes, I Talukdar, M Kowshik - International Journal of …, 2024 - Elsevier
Efficient and safe gene delivery is vital for genetic manipulation of stem cells for regenerative
medicine. Gold nanoparticles have been used for various biomedical applications in the …
medicine. Gold nanoparticles have been used for various biomedical applications in the …