The inflammatory disorders collectively termed the seronegative spondyloarthropathies
(SpA) include ankylosing spondylitis (AS), psoriatic arthritis (PsA), reactive arthritis, the …

Bilobalide is a natural sesquiterpene trilactone from Ginkgo biloba leaves. It has good water
solubility and is widely used in food and pharmaceutical fields. In the last decade, a plethora …

Objectives Murine models of interleukin (IL)-23-driven spondyloarthritis (SpA) have
demonstrated entheseal accumulation of γδT-cells which were responsible for the majority …

The involvement of IL-17A in autoimmune and inflammatory diseases has prompted the
development of therapeutic strategies to block the Th17 pathway. Promising results came …

The term spondyloarthritis pertains to both axial and peripheral arthritis including ankylosing
spondylitis (AS) and psoriatic arthritis (PsA), which is strongly linked to psoriasis and also …

Immune-related adverse events (irAEs) are a major concern when treating cancer patients
with immune checkpoint inhibitor (ICI) therapy. Selecting the most appropriate management …

Abstract Meteorin-like (IL-41), is a novel cytokine that is thought to be immunoregulatory and
is highly expressed in psoriatic skin. We investigated IL-41 protein expression in synovial …

The breadth of bone lesion types seen in spondyloarthritis is unprecedented in medicine
and includes increased bone turnover, bone loss and fragility, osteitis, osteolysis and …

Large granular lymphocytic leukemia (LGLL) is a lymphoproliferative disorder of older adults
characterized by the clonal expansion of cytotoxic T/natural killer cells due to constitutive pro …

Objectives Many patients with axial spondyloarthritis (axSpA) report persistent pain even
when treated with anti-inflammatory agents. Our aim was to explore the presence of central …