Epidemiology and risk-stratification of NAFLD-associated HCC
GN Ioannou - Journal of hepatology, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is projected to become the leading cause of
hepatocellular carcinoma (HCC) in many countries. Many risk factors for NAFLD are also …
hepatocellular carcinoma (HCC) in many countries. Many risk factors for NAFLD are also …
Non-alcoholic fatty liver disease: metabolic, genetic, epigenetic and environmental risk factors
O Juanola, S Martínez-López, R Francés… - International journal of …, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is one of the most frequent causes of chronic liver
disease in the Western world, probably due to the growing prevalence of obesity, metabolic …
disease in the Western world, probably due to the growing prevalence of obesity, metabolic …
Update on NAFLD genetics: from new variants to the clinic
Non-alcoholic fatty liver disease (NAFLD) is the leading cause of liver diseases in high-
income countries and the burden of NAFLD is increasing at an alarming rate. The risk of …
income countries and the burden of NAFLD is increasing at an alarming rate. The risk of …
Immunological mechanisms and therapeutic targets of fatty liver diseases
Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are the two major
types of chronic liver disease worldwide. Inflammatory processes play key roles in the …
types of chronic liver disease worldwide. Inflammatory processes play key roles in the …
Nonalcoholic fatty liver disease in adults: current concepts in etiology, outcomes, and management
T Marjot, A Moolla, JF Cobbold, L Hodson… - Endocrine …, 2020 - academic.oup.com
Nonalcoholic fatty liver disease (NAFLD) is a spectrum of disease, extending from simple
steatosis to inflammation and fibrosis with a significant risk for the development of cirrhosis. It …
steatosis to inflammation and fibrosis with a significant risk for the development of cirrhosis. It …
[PDF][PDF] Combined Effect of PNPLA3, TM6SF2, and HSD17B13 Variants on Risk of Cirrhosis and Hepatocellular Carcinoma in the General Population
H Gellert‐Kristensen, TG Richardson… - …, 2020 - Wiley Online Library
Background and Aims We hypothesized that a genetic risk score (GRS) for fatty liver disease
influences the risk of cirrhosis and hepatocellular carcinoma (HCC). Three genetic variants …
influences the risk of cirrhosis and hepatocellular carcinoma (HCC). Three genetic variants …
MAFLD vs. NAFLD: shared features and potential changes in epidemiology, pathophysiology, diagnosis, and pharmacotherapy
YX Xian, JP Weng, F Xu - Chinese medical journal, 2021 - mednexus.org
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide, placing an increasing burden on human health. NAFLD is a complex …
worldwide, placing an increasing burden on human health. NAFLD is a complex …
the emerging role of genetics in precision medicine for patients with non‐alcoholic steatohepatitis
B Carlsson, D Lindén, G Brolén… - Alimentary …, 2020 - Wiley Online Library
Background Non‐alcoholic steatohepatitis (NASH) is a severe form of non‐alcoholic fatty
liver disease (NAFLD) characterised by liver fat accumulation, inflammation and progressive …
liver disease (NAFLD) characterised by liver fat accumulation, inflammation and progressive …
Biomarkers for hepatobiliary cancers
JC Nault, A Villanueva - Hepatology, 2021 - Wiley Online Library
The clinical management of primary liver cancers such as hepatocellular carcinoma (HCC)
and cholangiocarcinoma (CCA) has significantly changed in the last 3 years. The …
and cholangiocarcinoma (CCA) has significantly changed in the last 3 years. The …
Common genetic variation in alcohol-related hepatocellular carcinoma: a case-control genome-wide association study
Background Hepatocellular carcinoma is a frequent consequence of alcohol-related liver
disease, with variable incidence among heavy drinkers. We did a genome-wide association …
disease, with variable incidence among heavy drinkers. We did a genome-wide association …