Biomarkers in breast cancer: an old story with a new end

L Neves Rebello Alves, D Dummer Meira… - Genes, 2023 - mdpi.com
Breast cancer is the second most frequent cancer in the world. It is a heterogeneous disease
and the leading cause of cancer mortality in women. Advances in molecular technologies …

miR-125 in Breast Cancer Etiopathogenesis: An Emerging Role as a Biomarker in Differential Diagnosis, Regenerative Medicine, and the Challenges of Personalized …

R Piergentili, E Marinelli, G Cucinella, A Lopez… - Non-coding RNA, 2024 - mdpi.com
Breast Cancer (BC) is one of the most common cancer types worldwide, and it is
characterized by a complex etiopathogenesis, resulting in an equally complex classification …

A Comprehensive Bioinformatics Approach to Identify Molecular Signatures and Key Pathways for the Huntington Disease

TM Meem, U Khan, MBR Mredul… - … and Biology Insights, 2023 - journals.sagepub.com
Huntington disease (HD) is a degenerative brain disease caused by the expansion of CAG
(cytosine-adenine-guanine) repeats, which is inherited as a dominant trait and progressively …

Comparative transcriptome analysis of MDBK cells reveals that BoIFN-γ augmented host immune responses to bovine herpesvirus 1 infection

B Jiang, J Wang, W Liu, J Cheng, J Xu… - Frontiers in …, 2022 - frontiersin.org
Bovine herpesvirus 1 (BoHV-1) is an alphaherpesvirus that causes infectious bovine
rhinotracheitis and infectious pustular vulvovaginitis in cattle. Ιnterferon-gamma (IFN-γ) is a …

Bioinformatics and system biology techniques to determine biomolecular signatures and pathways of prion disorder

MBR Mredul, U Khan, HK Rana… - … and Biology Insights, 2022 - journals.sagepub.com
Prion disorder (PD) is caused by misfolding and the formation of clumps of proteins in the
brain, notably Prion proteins resulting in a steady decrease in brain function. Early detection …

Improved ReliefF-based feature selection algorithm for cancer histology

J Liu, L Zhao, C Si, H Guan, X Dong - Biomedical Signal Processing and …, 2023 - Elsevier
Global cancer statistics show that breast cancer accounts for 11.6% of mortality, second only
to lung cancer, and is the second most deadly disease in the world. Due to the frequent …

BRCA1 interactors, RAD50 and BRIP1, as prognostic markers for triple-negative breast cancer severity

MN Katheeja, SP Das, R Das, S Laha - Frontiers in Genetics, 2023 - frontiersin.org
Introduction: BRIP1 (BRCA1-interacting protein 1) is one of the major interacting partners of
BRCA1, which plays an important role in repair by homologous recombination (HR). This …

Lung Adenocarcinoma Systems Biomarker and Drug Candidates Identified by Machine Learning, Gene Expression Data, and Integrative Bioinformatics Pipeline

SM Soyer, P Ozbek, C Kasavi - OMICS: A Journal of Integrative …, 2024 - liebertpub.com
Lung adenocarcinoma (LUAD) is a significant planetary health challenge with its high
morbidity and mortality rate, not to mention the marked interindividual variability in treatment …

Comprehensive analysis of INTS family related to expression, prognosis, diagnosis and immune features in hepatocellular carcinoma

B Wang, Z Du, CS Lin, D Liu, J Guo, J Shi, X Wang - Heliyon, 2024 - cell.com
Purpose The integrator subunit (INTS) family, a group exclusive to metazoans, participates
in various biologic processes. However, their roles in hepatocellular carcinoma (HCC) …

Insights into the Oncogenic, Prognostic, and Immunological Role of BRIP1 in Pan‐Cancer: A Comprehensive Data‐Mining‐Based Study

Y Liu, X Wu, Y Feng, Q Jiang, S Zhang… - Journal of …, 2023 - Wiley Online Library
Background. BRCA1 interacting helicase 1 (BRIP1), an ATP‐dependent DNA helicase
which belongs to an Iron‐Sulfur (Fe‐S) helicase cluster family with a DEAH domain, plays a …