Chagas disease persists as a global public health problem due to the high morbidity and
mortality burden. Despite the possibility of a cure and advances in transmission control …

Introduction Chagas disease, caused by parasite Trypanosoma cruzi, is the most important
neglected tropical disease in the Americas. Two drugs are available for treatment, but …

Trypanosoma cruzi, the protozoan causative of Chagas disease (ChD), exhibits striking
genetic and phenotypic intraspecific diversity, along with ecoepidemiological complexity …

Chagas disease (CD) is a vector-borne Neglected Zoonotic Disease (NZD) caused by a
flagellate protozoan, Trypanosoma cruzi, that affects various mammalian species across …

Trypanosoma cruzi, the causal agent of Chagas disease, is mainly transmitted by insects of
the Triatominae subfamily. In Colombia, there are 26 triatomine species, and 16 of them are …

Chagas disease is a neglected tropical disease caused by the protozoan Trypanosoma
cruzi. Benznidazole and nifurtimox are the two approved drugs for their treatment, but both …

Background Trypanosoma cruzi, the agent of Chagas disease, displays a highly structured
population, with multiple strains that can be grouped into 6–7 evolutionary lineages showing …

Chagas disease, initiated by the etiological agent Trypanosoma cruzi, is an endemic
infection in the American continent. Although vectorial transmission of T. cruzi is recognized …

Chagas disease is a neglected tropical disease that affects more than 8 million people.
Although there are therapies against this disease, the search for new drugs is important …

Since the first published genome sequence of Trypanosoma cruzi in 2005, there have been
tremendous technological advances in genomics, reverse genetics, and assay development …