The neurobiology of irritable bowel syndrome

EA Mayer, HJ Ryu, RR Bhatt - Molecular psychiatry, 2023 - nature.com
Irritable bowel syndrome (IBS) is the most prevalent disorder of brain-gut interactions that
affects between 5 and 10% of the general population worldwide. The current symptom …

Towards a systems view of IBS

EA Mayer, JS Labus, K Tillisch, SW Cole… - Nature Reviews …, 2015 - nature.com
Despite an extensive body of reported information about peripheral and central mechanisms
involved in the pathophysiology of IBS symptoms, no comprehensive disease model has …

Role of brain imaging in disorders of brain–gut interaction: a Rome Working Team Report

EA Mayer, J Labus, Q Aziz, I Tracey, L Kilpatrick… - Gut, 2019 - gut.bmj.com
Imaging of the living human brain is a powerful tool to probe the interactions between brain,
gut and microbiome in health and in disorders of brain–gut interactions, in particular IBS …

[HTML][HTML] Cognitive behavioral approach to understanding irritable bowel syndrome

G Hauser, S Pletikosic, M Tkalcic - World Journal of …, 2014 - ncbi.nlm.nih.gov
Irritable bowel syndrome (IBS) is considered a biopsychosocial disorder, whose onset and
precipitation are a consequence of interaction among multiple factors which include motility …

Altered brain responses in subjects with irritable bowel syndrome during cued and uncued pain expectation

JY Hong, B Naliboff, JS Labus, A Gupta… - …, 2016 - Wiley Online Library
Background A majority of the subjects with irritable bowel syndrome (IBS) show increased
behavioral and brain responses to expected and delivered aversive visceral stimuli during …

Cognitive impairment in irritable bowel syndrome (IBS): A systematic review

NCY Lam, HY Yeung, WK Li, HY Lo, CF Yuen… - Brain research, 2019 - Elsevier
Abstract Background Irritable Bowel Syndrome (IBS) is a common functional gastrointestinal
disorder which is characterized by altered bowel habits. A growing number of studies …

Increased attentional network functioning related to symptom severity measures in females with irritable bowel syndrome

CS Hubbard, J Hong, Z Jiang, B Ebrat… - …, 2015 - Wiley Online Library
Background Increased attention to gastrointestinal (GI) symptoms and disease‐specific
contexts may play an important role in the enhanced perception of visceral stimuli frequently …

Psychopathological and neuropsychological disorders associated with chronic primary visceral pain: Systematic review

A Arévalo-Martínez, JM Moreno-Manso… - Frontiers in …, 2022 - frontiersin.org
The World Health Organization (WHO), in its last review of its International Classification of
Diseases, established a new classification for chronic pain. Among the principal categories …

Electrophysiological investigation of the contribution of attention to altered pain inhibition processes in patients with irritable bowel syndrome

N Rustamov, A Wagenaar-Tison, E Doyer… - The Journal of …, 2020 - Springer
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder associated with
chronic abdominal pain and altered pain processing. The aim of this study was to examine …

Nature and specificity of altered cognitive functioning in IBS

KMF Wong, ADP Mak, SY Yuen… - …, 2019 - Wiley Online Library
Background It is unknown whether cognitive dysfunction found in patients with irritable
bowel syndrome (IBS) was attributable to the different subtypes, ongoing pathophysiological …