Considering the fundamental role of protein kinases in the mechanism of protein
phosphorylation in critical cellular processes, their dysregulation, especially in cancers, has …

Because genetic alterations including mutations, overexpression, translocations, and
dysregulation of protein kinases are involved in the pathogenesis of many illnesses, this …

Acute myeloid leukemia (AML) is a highly aggressive illness distinguished by the
accumulation of abnormal hematopoietic precursors in both the bone marrow and peripheral …

Fms-like tyrosine kinase 3 (FLT3) mutation mechanisms are among the most common
genetic abnormalities detected in about 30% of acute myeloid leukemia (AML) patients …

Acute myeloid leukaemia (AML), typically a disease of elderly adults, affects 8 children per
million each year, with the highest paediatric incidence in infants aged 0–2 of 18 per million …

Phenolic plant constituents are well known for their health-promoting and cancer
chemopreventive properties, and products containing such constituents are therefore readily …

Acute myeloid leukemia (AML), as the most common malignancy of the hematopoietic
system, poses challenges in treatment efficacy, relapse, and drug resistance. In this study …

Introduction Approximately one-third of all AML patients have a mutation in the Fms-like
tyrosine kinase 3 (FLT3) gene, which is associated with a poor prognosis in these …

Acute myeloid leukemia (AML), a heterogeneous hematologic malignancy, has generally a
poor prognosis despite the recent advancements in diagnostics and treatment. Genetic …

Due to the important role of protein kinases in protein phosphorylation within vital cellular
processes, their abnormal function, especially in cancer situations, has underscored their …