Rab32 family proteins regulate autophagosomal components recycling

Z Wu, H Que, C Li, L Yan, S Wang, Y Rong - Journal of Cell Biology, 2024 - rupress.org
In autophagy, autophagosomes deliver the lumenal contents to lysosomes for degradation
via autophagosome–lysosome fusion. In contrast, autophagosome outer membrane …

[HTML][HTML] Hermansky-Pudlak syndrome type 1 causes impaired anti-microbial immunity and inflammation due to dysregulated immunometabolism

A Cavounidis, S Pandey, M Capitani, M Friedrich… - Mucosal …, 2022 - Elsevier
Hermansky-Pudlak syndrome (HPS) types 1 and 4 are caused by defective vesicle
trafficking. The mechanism for Crohn's disease-like inflammation, lung fibrosis, and …

Mitochondrial A‐kinase anchoring proteins in cardiac ventricular myocytes

RT Sherpa, C Fiore, KS Moshal… - Physiological …, 2021 - Wiley Online Library
Compartmentation of cAMP signaling is a critical factor for maintaining the integrity of
receptor‐specific responses in cardiac myocytes. This phenomenon relies on various factors …

Determination of the Salmonella intracellular lifestyle by the diversified interaction of Type III secretion system effectors and host GTPases

K Meng, P Zhu, L Shi, S Li - WIREs Mechanisms of Disease, 2023 - Wiley Online Library
Intracellular bacteria have developed sophisticated strategies to subvert the host
endomembrane system to establish a stable replication niche. Small GTPases are critical …

Dot/Icm-dependent restriction of Legionella pneumophila within neutrophils

CTD Price, HE Hanford, A Vashishta, M Ozanic… - Mbio, 2021 - Am Soc Microbiol
ABSTRACT The Dot/Icm type IV secretion system (T4SS) of Legionella pneumophila is
essential for lysosomal evasion and permissiveness of macrophages for intracellular …