Recent strategies for improving MALDI mass spectrometry imaging performance towards low molecular weight compounds
Z Sun, F Wang, Y Liu, B Deng, R Ren, Y Wang… - TrAC Trends in …, 2024 - Elsevier
Matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI),
traditionally used for analyzing larger molecules, faces challenges with low molecular …
traditionally used for analyzing larger molecules, faces challenges with low molecular …
Ultrahigh-Mass Resolution Mass Spectrometry Imaging with an Orbitrap Externally Coupled to a High-Performance Data Acquisition System
A Grgic, KO Nagornov, AN Kozhinov… - Analytical …, 2023 - ACS Publications
Matrix-assisted laser desorption ionization (MALDI) mass spectrometry imaging (MSI) is a
powerful analytical tool that enables molecular sample analysis while simultaneously …
powerful analytical tool that enables molecular sample analysis while simultaneously …
Untargeted Spatial Metabolomics and Spatial Proteomics on the Same Tissue Section
GW Vandergrift, M Veličković, LZ Day… - Analytical …, 2024 - ACS Publications
An increasing number of spatial multiomic workflows have recently been developed. Some
of these approaches have leveraged initial mass spectrometry imaging (MSI)-based spatial …
of these approaches have leveraged initial mass spectrometry imaging (MSI)-based spatial …
Experimental and Computational Evaluation of Lipidomic In-Source Fragmentation as a Result of Postionization with Matrix-Assisted Laser Desorption/Ionization
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) can
provide spatially resolved molecular information about a sample. Recently, a postionization …
provide spatially resolved molecular information about a sample. Recently, a postionization …
Effects of Sex and Western Diet on Spatial Lipidomic Profiles for the Hippocampus, Cortex, and Corpus Callosum in Mice Using MALDI MSI
CC Shafer, J Di Lucente, UR Mendiola… - Journal of the …, 2024 - ACS Publications
Diet is inextricably linked to human health and biological functionality. Reduced cognitive
function among other health issues has been correlated with a western diet (WD) in mouse …
function among other health issues has been correlated with a western diet (WD) in mouse …
External Data Systems Enable Enhanced (and Sustainable) Fourier Transform Mass Spectrometry Imaging for Legacy Hybrid Linear Ion Trap–Orbitrap Platforms
FE Leach III, KO Nagornov, AN Kozhinov… - Journal of the …, 2024 - ACS Publications
Legacy Fourier transform (FT) mass spectrometers provide robust platforms for bioanalytical
mass spectrometry (MS) yet lack the most modern performance capabilities. For many …
mass spectrometry (MS) yet lack the most modern performance capabilities. For many …
Evaluation of atmospheric-plasma-source absorption mode Fourier transform Orbitrap mass spectrometry for chlorinated paraffin mixtures
C Masucci, KO Nagornov, AN Kozhinov, K Kraft… - Analytical and …, 2024 - Springer
Chlorinated paraffins (CP) are complex molecular mixtures occurring in a wide range of
isomers and homologs of environmental hazards, whose analytical complexity demand …
isomers and homologs of environmental hazards, whose analytical complexity demand …
Deep MALDI-MS Spatial Omics guided by Quantum Cascade Laser Mid-infrared Imaging Microscopy
L Gruber, S Schmidt, T Enzlein, HG Vo, JL Cairns… - bioRxiv, 2023 - biorxiv.org
In spatial omics, highly confident molecular identifications are indispensable for the
investigation of complex biology and for spatial biomarker discovery. However, current mass …
investigation of complex biology and for spatial biomarker discovery. However, current mass …