Members of the major facilitator superfamily (MFS) of transport proteins are essential for the
movement of a wide range of substrates across biomembranes. As this transport requires a …

The ancient and ubiquitous major facilitator superfamily (MFS) represents the largest
secondary transporter family and plays a crucial role in a multitude of physiological …

Glucose is the primary fuel to life on earth. Cellular uptake of glucose is a fundamental
process for metabolism, growth, and homeostasis. Three families of secondary glucose …

The major facilitator superfamily (MFS) is one of the two largest families of membrane
transporters found on Earth. It is present ubiquitously in bacteria, archaea, and eukarya and …

Glucose transporters are essential for metabolism of glucose in cells of diverse organisms
from microbes to humans, exemplified by the disease-related human proteins GLUT1, 2, 3 …

The major facilitator superfamily (MFS) is one of the largest groups of secondary active
transporters conserved from bacteria to humans. MFS proteins selectively transport a wide …

Multidrug efflux systems display the ability to transport a variety of structurally unrelated
drugs from a cell and consequently are capable of conferring resistance to a diverse range …

Many transport proteins of bacteria and eukaryotes are thought to possess a common
structural motif of 12 transmembrane-spanning α-helical segments. In this report we use …

All known d-xylose transporters are competitively inhibited by d-glucose, which is one of the
major reasons hampering simultaneous fermentation of d-glucose and d-xylose, two primary …

Cancerous cells have an acutely increased demand for energy, leading to increased levels
of human glucose transporter 1 (hGLUT1). This up-regulation suggests hGLUT1 as a target …