[HTML][HTML] The Immunomodulatory Role of Vitamin D in Regulating the Th17/Treg Balance and Epithelial–Mesenchymal Transition: A Hypothesis for Gallbladder Cancer

R Cartes-Velásquez, A Vera, R Torres-Quevedo… - Nutrients, 2024 - mdpi.com
The etiology of gallbladder cancer (GBC) is multifactorial, with chronic inflammation resulting
from infections, autoimmune diseases, and lifestyle factors playing a pivotal role. Vitamin D …

Targeting the Endothelin-1 pathway to reduce invasion and chemoresistance in gallbladder cancer cells

F Rodas, JA Vidal-Vidal, D Herrera… - Cancer Cell …, 2023 - Springer
Background Gallbladder cancer (GBC) is a prevalent and deadly biliary tract carcinoma,
often diagnosed at advanced stages with limited treatment options. The 5-year survival rate …

Global variations in gallbladder cancer incidence: What do recorded data and national estimates tell us?

M Piñeros, J Vignat, M Colombet… - … Journal of Cancer, 2024 - Wiley Online Library
On a global scale, gallbladder cancer is a relatively rare cancer with a striking variability in
incidence across countries and world regions. We examined recent geographic variations …

Distinct Driver Pathway Enrichments and a High Prevalence of TSC2 Mutations in Right Colon Cancer in Chile: A Preliminary Comparative Analysis

C Tapia-Valladares, G Valenzuela, E González… - International Journal of …, 2024 - mdpi.com
Colorectal cancer (CRC) is the second leading cause of cancer deaths globally. While
ethnic differences in driver gene mutations have been documented, the South American …

Scientists and scientific journals should adhere to ethical standards for the use and reporting of data from Indigenous people

J Yracheta, T Morriseau, K Dale, A Gerth, J McGavock - Diabetologia, 2024 - Springer
Internationally, governments and scientists are bound by legal and treaty rights when
working with Indigenous nations. These rights include the right of Indigenous people to …

Clinical and Genomic Characterization of ERBB2-Altered Gallbladder Cancer: Exploring Differences Between an American and a Chilean Cohort

S Mondaca, H Walch, S Sepúlveda, N Schultz… - JCO Global …, 2024 - ascopubs.org
PURPOSE Gallbladder cancer (GBC) is a biliary tract malignancy characterized by its high
lethality. Although the incidence of GBC is low in most countries, specific areas such as …

[HTML][HTML] Inbreeding and Gallbladder Cancer Risk: Homozygosity Associations Adjusted for Indigenous American Ancestry, BMI, and Genetic Risk of Gallstone Disease

F Ceballos, F Boekstegers, D Scherer… - Cancers, 2024 - mdpi.com
Latin Americans have a rich genetic make-up that translates into heterogeneous fractions of
the autosomal genome in runs of homozygosity (FROH) and heterogeneous types and …

Distinct Driver Pathway Enrichments and a High Prevalence of TSC2 Mutations in Right Colon Cancer in Chile: A Preliminary Comparative Analysis

C Tapia, G Valenzuela, E González, I Maureira, J Toro… - 2024 - repositorio.udd.cl
Colorectal cancer (CRC) is the second leading cause of cancer deaths globally. While
ethnic differences in driver gene mutations have been documented, the South American …

Cáncer de vesícula:¿ Es momento de modificar el GES?

CPS Sanhueza, X De Aretxabala… - … Médica de Chile, 2024 - revistamedicadechile.cl
Chile currently has one of the highest mortality rates from gallbladder cancer in the world. In
2006, the Chilean Ministry of Health included cholelithiasis (patients aged 35-49) and …

[HTML][HTML] Desafío del cáncer de vesícula biliar: Un llamado a la investigación

N Apuril Céspedes - Anales de la Facultad de Ciencias Médicas …, 2024 - scielo.iics.una.py
En el panorama de la oncología, el cáncer de vesícula biliar ha permanecido durante
mucho tiempo en las sombras, eclipsado por otras formas más comunes de cáncer. Sin …