The complement system is a part of the immune system and consists of multiple complement
components with biological functions such as defense against pathogens and …

As one of the cornerstones of innate immunity, the complement system has long been
implicated in the pathogenesis of atherosclerosis. Growing evidence demonstrates the …

Although tuberculosis (TB) causes more deaths than any other pathogen, most infected
individuals harbor the pathogen without signs of disease. We explored the metabolome of> …

Objective: Plasma total HDL (high-density lipoprotein) is a heterogeneous mix of many
protein-based subspecies whose functions and associations with coronary heart disease …

The complement system has been implicated in obesity, fatty liver, diabetes and
cardiovascular disease (CVD). Complement factors are produced in adipose tissue and …

Atherosclerosis is a chronic inflammatory disease and the complement system plays a
central role in innate immunity. Increasing evidence exists that the complement system is …

Objective: HDL (high-density lipoprotein) contains functional proteins that define single
subspecies, each comprising 1% to 12% of the total HDL. We studied the differential …

This review summarizes available evidence on the role of serum complement component 3
(C3), produced by liver, adipocytes and activated macrophages at inflammation sites, and …

A wealth of evidence indicates a fundamental role for inflammation in the pathogenesis of
cardiovascular disease (CVD), contributing to the development and progression of …

Chronic inflammatory diseases, such as rheumatoid arthritis, steatohepatitis, periodontitis,
chronic kidney disease, and others are associated with an increased risk of atherosclerotic …