A catalogue of signal molecules that interact with sensor kinases, chemoreceptors and transcriptional regulators

MA Matilla, F Velando, D Martín-Mora… - FEMS Microbiology …, 2022 - academic.oup.com
Bacteria have evolved many different signal transduction systems that sense signals and
generate a variety of responses. Generally, most abundant are transcriptional regulators …

The effect of bacterial chemotaxis on host infection and pathogenicity

MA Matilla, T Krell - FEMS Microbiology Reviews, 2018 - academic.oup.com
Chemotaxis enables microorganisms to move according to chemical gradients. Although
this process requires substantial cellular energy, it also affords key physiological benefits …

Anaerobic catabolism of aromatic compounds: a genetic and genomic view

M Carmona, MT Zamarro, B Blázquez… - Microbiology and …, 2009 - Am Soc Microbiol
Aromatic compounds belong to one of the most widely distributed classes of organic
compounds in nature, and a significant number of xenobiotics belong to this family of …

Bacterial sensor kinases: diversity in the recognition of environmental signals

T Krell, J Lacal, A Busch… - Annual review of …, 2010 - annualreviews.org
Bacteria sense and respond to a wide range of physical and chemical signals. Central to
sensing and responding to these signals are two-component systems, which have a sensor …

Diversity in sensing and signaling of bacterial sensor histidine kinases

E Ishii, Y Eguchi - Biomolecules, 2021 - mdpi.com
Two-component signal transduction systems (TCSs) are widely conserved in bacteria to
respond to and adapt to the changing environment. Since TCSs are also involved in …

Antimicrobial resistance: progress and challenges in antibiotic discovery and anti‐infective therapy

T Krell, MA Matilla - Microbial Biotechnology, 2022 - Wiley Online Library
The alarming rise in the emergence of antimicrobial resistance in human, animal and plant
pathogens is challenging global health and food production. Traditional strategies used for …

[HTML][HTML] Histidine kinases and the missing phosphoproteome from prokaryotes to eukaryotes

K Adam, T Hunter - Laboratory Investigation, 2018 - Elsevier
Protein phosphorylation is the most common type of post-translational modification in
eukaryotes. The phosphoproteome is defined as the complete set of experimentally …

Identification of a chemoreceptor for tricarboxylic acid cycle intermediates: differential chemotactic response towards receptor ligands

J Lacal, C Alfonso, X Liu, RE Parales, B Morel… - Journal of Biological …, 2010 - ASBMB
We report the identification of McpS as the specific chemoreceptor for 6 tricarboxylic acid
(TCA) cycle intermediates and butyrate in Pseudomonas putida. The analysis of the …

The dCache chemoreceptor TlpA of Helicobacter pylori binds multiple attractant and antagonistic ligands via distinct sites

KS Johnson, BA Elgamoudi, FEC Jen, CJ Day… - MBio, 2021 - Am Soc Microbiol
ABSTRACT The Helicobacter pylori chemoreceptor TlpA plays a role in dampening host
inflammation during chronic stomach colonization. TlpA has a periplasmic dCache_1 …

Bacterial chemotaxis towards aromatic hydrocarbons in Pseudomonas

J Lacal, F Muñoz‐Martínez… - Environmental …, 2011 - Wiley Online Library
Bacterial chemotaxis is an adaptive behaviour, which requires sophisticated information‐
processing capabilities that cause motile bacteria to either move towards or flee from …