Lymphatic filariasis and onchocerciasis

MJ Taylor, A Hoerauf, M Bockarie - The Lancet, 2010 - thelancet.com
Lymphatic filariasis and onchocerciasis are parasitic helminth diseases that constitute a
serious public health issue in tropical regions. The filarial nematodes that cause these …

Effect of helminth-induced immunity on infections with microbial pathogens

P Salgame, GS Yap, WC Gause - Nature immunology, 2013 - nature.com
Helminth infections are ubiquitous worldwide and can trigger potent immune responses that
differ from and potentially antagonize host protective responses to microbial pathogens. In …

Helminth-tuberculosis co-infection: an immunologic perspective

S Babu, TB Nutman - Trends in immunology, 2016 - cell.com
Over 2 billion people worldwide are infected with helminths (worms). Similarly, infection with
Mycobacterium tuberculosis (Mtb) occurs in over a third of the world's population, often with …

Fasciola hepatica is associated with the failure to detect bovine tuberculosis in dairy cattle

J Claridge, P Diggle, CM McCann, G Mulcahy… - Nature …, 2012 - nature.com
Bovine tuberculosis (BTB) is a significant and intractable disease of cattle caused by
Mycobacterium bovis. In the United Kingdom, despite an aggressive eradication …

Tuberculosis comorbidity with communicable and noncommunicable diseases

M Bates, BJ Marais, A Zumla - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
The 18th WHO Global Tuberculosis Annual Report indicates that there were an estimated
8.6 million incident cases of tuberculosis (TB) in 2012, which included 2.9 million women …

Uninfected but not unaffected: chronic maternal infections during pregnancy, fetal immunity, and susceptibility to postnatal infections

N Dauby, T Goetghebuer, TR Kollmann… - The Lancet infectious …, 2012 - thelancet.com
Chronic infections during pregnancy are highly prevalent in some parts of the world.
Infections with helminths, Trypanosoma cruzi, Plasmodium spp, and HIV might affect the …

Modulation of specific and allergy‐related immune responses by helminths

E Daniłowicz-Luebert, NL O′ Regan… - BioMed Research …, 2011 - Wiley Online Library
Helminths are master regulators of host immune responses utilising complex mechanisms to
dampen host protective Th2‐type responses and favour long‐term persistence. Such …

The extent, nature, and pathogenic consequences of helminth polyparasitism in humans: A meta-analysis

RE Donohue, ZK Cross, E Michael - PLoS neglected tropical …, 2019 - journals.plos.org
Background Individual helminth infections are ubiquitous in the tropics; geographical
overlaps in endemicity and epidemiological reports suggest areas endemic for multiple …

Toll-like receptor signaling in parasitic infections

DS Ashour - Expert review of clinical immunology, 2015 - Taylor & Francis
The essential role played by Toll-like receptors (TLRs) during parasitic infections, as a part
of the innate immune response, has gained much attention. TLR-induced signaling …

Mycobacterium tuberculosis‐specific CD4+ T‐cell response is increased, and Treg cells decreased, in anthelmintic‐treated patients with latent TB

F Toulza, L Tsang, THM Ottenhoff… - European journal of …, 2016 - Wiley Online Library
In many settings, adults with active or latent tuberculosis will also be coinfected with
helminths. Our study aimed to investigate how anthelmintic treatment modulates …