Enantioselective synthesis through enzymatic asymmetrization

E Schoffers, A Golebiowski, CR Johnson - Tetrahedron, 1996 - Elsevier
During the last few decades almost no other aspect of organic synthesis has received as
much attention as the preparation of enantiomerically pure compounds. The synthesis of …

Stereoselective synthesis of 1, 3-diols

SE Bode, M Wolberg, M Mueller - Synthesis, 2006 - thieme-connect.com
Many polyketide-derived natural products contain a syn-or anti-1, 3-diol unit. No general and
simple approach exists for the flexible synthesis of polyols and other polyketide-derived …

[图书][B] Green chemistry and catalysis

RA Sheldon, I Arends, U Hanefeld - 2007 - books.google.com
This first book to focus on catalytic processes from the viewpoint of green chemistry presents
every important aspect:? Numerous catalytic reductions and oxidations methods? Solid-acid …

[图书][B] Hydrolases in organic synthesis: regio-and stereoselective biotransformations

UT Bornscheuer, RJ Kazlauskas - 2006 - books.google.com
From reviews to the first edtion:" Bornscheuer and Kazlauskas have set out, and succeeded,
in producing a definitive manual on hydrolytic enzymes (especially lipases, esterases, and …

Lipase-supported synthesis of biologically active compounds

F Theil - Chemical Reviews, 1995 - ACS Publications
The synthesis of organic compounds with one or several chirality centers is one of the most
challeng-ing tasks in modern organic synthesis. Among the possibilities to achieve …

Amphotericin B: 50 years of chemistry and biochemistry

DM Cereghetti, EM Carreira - Synthesis, 2006 - thieme-connect.com
The last century has seen the isolation and synthesis of a multitude of molecules with
remarkable biological activity. Some of them represent milestones in chemical space and …

[图书][B] Asymmetric synthetic methodology

DJ Ager, MB East - 2020 - taylorfrancis.com
This comprehensive text presents a critical discussion of the scopes and limitations of
various organic synthetic methodologies that are available for performing asymmetric …

[图书][B] Organoboranes for syntheses

PV Ramachandran, HC Brown - 2001 - ACS Publications
Organoboranes for Syntheses Page 1 ACS SYMPOSIUM SERIES 783 Organoboranes for
Syntheses PV Ramachandran, EDITOR Purdue University Herbert C. Brown, EDITOR Purdue …

Biocatalysis in the preparation of the statin side chain

A Liljeblad, A Kallinen, LT Kanerva - Current Organic Synthesis, 2009 - ingentaconnect.com
Statins used in the treatment of dyslipidemias are top-selling drugs in the world. Economical
production of statins in industrial scale is challenging, because the side chain of statins is a …

Practical large scale synthesis of tert-butyl (3R, 5S)-6-hydroxy-3, 5-O-isopropylidene-3, 5-dihydroxyhexanoate: essential building block for HMG-CoA reductase …

G Beck, H Jendralla, K Kesseler - Synthesis, 1995 - thieme-connect.com
In 1988, the biotechnologically produced fungal metabolite mevinolin (1) 1 was introduced
into medical therapy of hypercholesterolemia as Lovastatin (Mevacor®). Soon afterwards …