Immune privilege: the microbiome and uveitis

C Mölzer, J Heissigerova, HM Wilson… - Frontiers in …, 2021 - frontiersin.org
Immune privilege (IP), a term introduced to explain the unpredicted acceptance of allogeneic
grafts by the eye and the brain, is considered a unique property of these tissues. However …

Fostemsavir for the treatment of HIV

N Seval, C Frank, M Kozal - Expert Review of Anti-infective …, 2021 - Taylor & Francis
Introduction: For those with heavily treatment experienced (HTE) HIV-1 and virologic failure,
therapeutic options are limited. A variety of barriers such as drug resistance, side effects …

Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ART

M Pino, S Pereira Ribeiro, A Pagliuzza… - PLoS …, 2021 - journals.plos.org
Clinical outcomes are inferior for individuals with HIV having suboptimal CD4 T-cell recovery
during antiretroviral therapy (ART). We investigated if the levels of infection and the …

HIV-1 DNA and immune activation levels differ for long-lived T-cells in lymph nodes, compared with peripheral blood, during antiretroviral therapy

C Mallarino-Haeger, M Pino, EG Viox… - Journal of …, 2023 - Am Soc Microbiol
Elucidating the mechanisms underlying the persistence and location of the HIV reservoir is
critical for developing cure interventions. While it has been shown that levels of T-cell …

High circulating SDF-1and MCP-1 levels and genetic variations in CXCL12, CCL2 and CCR5: Prognostic signature of immune recovery status in treated HIV-positive …

E Yeregui, C Viladés, P Domingo, A Ceausu… - …, 2020 - thelancet.com
Background The underlying mechanisms of incomplete immune reconstitution in treated HIV-
positive patients are very complex and may be multifactorial, but perturbation of chemokine …

CD4/CD8 ratio and CD8+ T-cell count as prognostic markers for non-AIDS mortality in people living with HIV. A systematic review and meta-analysis

R Ron, J Martínez-Sanz, S Herrera… - Frontiers in …, 2024 - frontiersin.org
Background In people living with HIV (PLHIV), the CD4/CD8 ratio has been proposed as a
useful marker for non-AIDS events. However, its predictive ability on mortality over CD4 …

Immunovirological discordance among female sex workers who start antiretroviral therapy in Burkina Faso

WW Bazié, DY Somé, IT Traoré, A Sanon… - BMC infectious …, 2022 - Springer
Background In people living with HIV/AIDS (PLWHA), initiation of antiretroviral therapy (ART)
leads to sustained effective suppression of viral replication and increasing CD4+ T cell …

Cognitively Based Compassion Training for HIV Immune Nonresponders—An Attention-Placebo Randomized Controlled Trial

BK Titanji, M Tejani, EW Farber, CC Mehta… - JAIDS Journal of …, 2022 - journals.lww.com
Objective: Chronic inflammation is associated with increased morbidity and mortality for
people with HIV (PWH). Psychological stress is an important contributor to this chronic …

Association of Alcohol Consumption With CD4 Recovery After Antiretroviral Therapy Initiation in St. Petersburg, Russia

A McLaughlin, N Lin, W Jiang, S Lodi… - JAIDS Journal of …, 2023 - journals.lww.com
Background: Delayed CD4 recovery after initiating antiretroviral therapy (ART) is a novel
potential mechanism by which alcohol consumption leads to increased morbidity and …

Immune recovery after antiretroviral therapy initiation: a challenge for people living with HIV in Brazil

CCP Mendicino, EEM Moodie… - Cadernos de Saúde …, 2021 - SciELO Public Health
Immune recovery reflects health conditions. Our goal was to estimate the time it takes to
achieve immune recovery and its associated factors, in people living with HIV (PLHIV), after …