[HTML][HTML] The role of YKL-40 in the pathogenesis of autoimmune diseases: a comprehensive review

K Tizaoui, JW Yang, KH Lee, JH Kim… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Abstract YKL-40, a chitinase-3-like protein 1 (CHI3L1) or human cartilage glycoprotein 39
(HC gp-39), is expressed and secreted by various cell-types including macrophages …

YKL-40 as a novel biomarker in cardio-metabolic disorders and inflammatory diseases

Y Deng, G Li, D Chang, X Su - Clinica Chimica Acta, 2020 - Elsevier
Dyslipidaemia is associated with numerous health problems that include the combination of
insulin resistance, hypertension and obesity, ie, metabolic syndrome. Although the use of …

Nrf2 regulates CHI3L1 to suppress inflammation and improve post-traumatic osteoarthritis

Y Song, D Hao, H Jiang, M Huang, Q Du… - Journal of …, 2021 - Taylor & Francis
Introduction Post-traumatic osteoarthritis (PTOA) is an inflammatory condition that occurs
following mechanical joint trauma and that results in joint degeneration. This study sought to …

[PDF][PDF] RETRACTED: Silencing of Long Non-coding RNA HOTTIP Reduces Inflammation in Rheumatoid Arthritis by Demethylation of SFRP1

X Hu, J Tang, X Hu, P Bao, W Deng, J Wu… - … Therapy-Nucleic Acids, 2020 - cell.com
Accumulating evidence suggests long non-coding RNAs (lncRNAs) play crucial roles in the
pathogenesis of rheumatoid arthritis (RA). Here, we aimed to define the role of HOXA …

DUSP19 regulates IL-1β-induced apoptosis and MMPs expression in rat chondrocytes through JAK2/STAT3 signaling pathway

ZZ Yao, AX Hu, XS Liu - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Osteoarthritis (OA) is a disease with degeneration of articular cartilage and its development
and progression is characterized by chondrocyte apoptosis. To examine whether DUSP19 …

[HTML][HTML] YKL-40 serum levels are predicted by inflammatory state, age and diagnosis of idiopathic inflammatory myopathies

M Vázquez-Del Mercado, F Pérez-Vázquez… - Scientific Reports, 2023 - nature.com
YKL-40 increase according to the aging process, and its functions have been associated
with tissue remodeling and systemic inflammation. In Rheumatoid Arthritis (RA) it has been …

NF-κB-mediated inhibition of microRNA-149-5p regulates Chitinase-3-like 1 expression in human airway epithelial cells

K Hübner, D Karwelat, E Pietsch, I Beinborn… - Cellular …, 2020 - Elsevier
Lower respiratory tract infections are among the most common causes of death worldwide.
Main pathogens leading to these severe infections are viruses and gram-positive bacteria …

[HTML][HTML] Chitinase-3-like protein 1 (YKL-40): a new biomarker of inflammation in pyoderma gangrenosum

A Jankowska-Konsur, Ł Magdalena… - Acta dermato …, 2022 - ncbi.nlm.nih.gov
Pyoderma gangrenosum (PG) is a rare, neutrophilic dermatosis with unclear aetiopathology,
considered as an autoinflammatory disease, associated with other immune-mediated …

[PDF][PDF] The role of serum chitinase-3-like 1 protein (YKL-40) level and its correlation with proinflammatory cytokine in patients with rheumatoid arthritis

NUG Mohammed, FM Khaleel, FI Gorial - Baghdad Science Journal, 2022 - iasj.net
Chitinase-3-like 1 protein (YKL-40) is a glycoprotein primarily produced in the arthritic joint
and plays a crucial role in inflammatory processes. The aim of the study is to establish the …

[PDF][PDF] Nonsurgical Periodontal Therapy Reduces Salivary and Gingival Crevicular Fluid YKL-40 and IL-6 Levels in Chronic Periodontitis.

ZP Keles Yucel, GC Keles, B Avci… - Oral Health & Preventive …, 2020 - d-nb.info
Purpose: A novel acute-phase protein, YKL-40, is known as an inflammation-associated
glycoprotein. YKL-40 is shown to be linked to inflammation, endothelial dysfunction and …