Modified nucleotides in mRNA are an essential addition to the standard genetic code of four
nucleotides in animals, plants, and their viruses. The emerging field of epitranscriptomics …

Marker gene amplicon sequencing is often preferred over whole genome sequencing for
microbial community characterization, due to its lower cost while still enabling assessment of …

This study investigates transfer ribonucleic acid (tRNA) conformational dynamics in the
context of MELAS (mitochondrial encephalomyopathy, lactic acidosis, and stroke-like …

Ribonucleic acids (RNAs) are considered as effective and minimally invasive biomarkers for
disease diagnosis and prognosis due to their critical role in the regulation of different cellular …

Ovarian cancer is the most aggressive of all gynaecological malignancies and is the leading
cause of cancer-associated mortality worldwide. Over the recent years, there has been a …

Linking, or multicomponent topological entanglement, is ubiquitous in soft matter systems,
from mixtures of polymers and DNA filaments packed in vivo to interlocked line defects in …

Nanopores hold great potential for the analysis of complex biological molecules at the single-
entity level. One particularly interesting macromolecular machine is the ribosome …

Recent work has pushed the noise-limited bandwidths of solid-state nanopore conductance
recordings to more than 5 MHz and of ion channel conductance recordings to more than 500 …

Sequencing of the human genome has led to the definition of the genes for most of the
relevant blood group systems, and the polymorphisms responsible for most of the clinically …

Differences in tRNA expression have been implicated in a remarkable number of biological
processes. There is growing evidence that tRNA genes can play dramatically different roles …