[HTML][HTML] The bone extracellular matrix in bone formation and regeneration
X Lin, S Patil, YG Gao, A Qian - Frontiers in pharmacology, 2020 - frontiersin.org
Bone regeneration repairs bone tissue lost due to trauma, fractures, and tumors, or absent
due to congenital disorders. The extracellular matrix (ECM) is an intricate dynamic bio …
due to congenital disorders. The extracellular matrix (ECM) is an intricate dynamic bio …
[HTML][HTML] Mesenchymal stem cell perspective: cell biology to clinical progress
MF Pittenger, DE Discher, BM Péault… - NPJ Regenerative …, 2019 - nature.com
The terms MSC and MSCs have become the preferred acronym to describe a cell and a cell
population of multipotential stem/progenitor cells commonly referred to as mesenchymal …
population of multipotential stem/progenitor cells commonly referred to as mesenchymal …
Concise review: MSC-derived exosomes for cell-free therapy
DG Phinney, MF Pittenger - Stem cells, 2017 - academic.oup.com
Mesenchymal stem cell transplantation is undergoing extensive evaluation as a cellular
therapy in human clinical trials. Because MSCs are easily isolated and amenable to culture …
therapy in human clinical trials. Because MSCs are easily isolated and amenable to culture …
[HTML][HTML] Mesenchymal stem cells in fibrotic disease
Fibrosis is associated with organ failure and high mortality and is commonly characterized
by aberrant myofibroblast accumulation. Investigating the cellular origin of myofibroblasts in …
by aberrant myofibroblast accumulation. Investigating the cellular origin of myofibroblasts in …
The mesenchymal stromal cells dilemma—does a negative phase III trial of random donor mesenchymal stromal cells in steroid-resistant graft-versus-host disease …
J Galipeau - Cytotherapy, 2013 - Elsevier
The use of cryopreserved unmatched allogeneic mesenchymal stromal cells (MSCs) for
treatment of steroid-resistant graft-versus-host disease has become medical practice in …
treatment of steroid-resistant graft-versus-host disease has become medical practice in …
IDO-independent suppression of T cell effector function by IFN-γ–licensed human mesenchymal stromal cells
R Chinnadurai, IB Copland, SR Patel… - The Journal of …, 2014 - journals.aai.org
Human bone marrow–derived mesenchymal stromal cells (MSCs) inhibit proliferation of
activated T cells, and IFN-γ plays an important role in this process. This IFN-γ–licensed veto …
activated T cells, and IFN-γ plays an important role in this process. This IFN-γ–licensed veto …
Tightly anchored tissue-mimetic matrices as instructive stem cell microenvironments
MC Prewitz, FP Seib, M Von Bonin, J Friedrichs… - Nature …, 2013 - nature.com
A major obstacle in defining the exact role of extracellular matrix (ECM) in stem cell niches is
the lack of suitable in vitro methods that recapitulate complex ECM microenvironments. Here …
the lack of suitable in vitro methods that recapitulate complex ECM microenvironments. Here …
[HTML][HTML] Comprehensive proteomic analysis of exosome mimetic vesicles and exosomes derived from human umbilical cord mesenchymal stem cells
Z Zhang, T Mi, L Jin, M Li, C Zhanghuang… - Stem cell research & …, 2022 - Springer
Background Exosomes derived from mesenchymal stem cells (MSCs) have shown to have
effective application prospects in the medical field, but exosome yield is very low. The …
effective application prospects in the medical field, but exosome yield is very low. The …
[HTML][HTML] Osteogenic differentiation of MSC through calcium signaling activation: transcriptomics and functional analysis
F Viti, M Landini, A Mezzelani, L Petecchia, L Milanesi… - PloS one, 2016 - journals.plos.org
The culture of progenitor mesenchymal stem cells (MSC) onto osteoconductive materials to
induce a proper osteogenic differentiation and mineralized matrix regeneration represents a …
induce a proper osteogenic differentiation and mineralized matrix regeneration represents a …
Paracrine effects of mesenchymal stem cells in ischemic stroke: Opportunities and challenges
It is well acknowledged that neuroprotective effects of transplanted mesenchymal stem cells
(MSCs) in ischemic stroke are attributed to their paracrine-mediated actions or bystander …
(MSCs) in ischemic stroke are attributed to their paracrine-mediated actions or bystander …