Bone regeneration repairs bone tissue lost due to trauma, fractures, and tumors, or absent
due to congenital disorders. The extracellular matrix (ECM) is an intricate dynamic bio …

The terms MSC and MSCs have become the preferred acronym to describe a cell and a cell
population of multipotential stem/progenitor cells commonly referred to as mesenchymal …

Mesenchymal stem cell transplantation is undergoing extensive evaluation as a cellular
therapy in human clinical trials. Because MSCs are easily isolated and amenable to culture …

Fibrosis is associated with organ failure and high mortality and is commonly characterized
by aberrant myofibroblast accumulation. Investigating the cellular origin of myofibroblasts in …

The use of cryopreserved unmatched allogeneic mesenchymal stromal cells (MSCs) for
treatment of steroid-resistant graft-versus-host disease has become medical practice in …

Human bone marrow–derived mesenchymal stromal cells (MSCs) inhibit proliferation of
activated T cells, and IFN-γ plays an important role in this process. This IFN-γ–licensed veto …

A major obstacle in defining the exact role of extracellular matrix (ECM) in stem cell niches is
the lack of suitable in vitro methods that recapitulate complex ECM microenvironments. Here …

Background Exosomes derived from mesenchymal stem cells (MSCs) have shown to have
effective application prospects in the medical field, but exosome yield is very low. The …

The culture of progenitor mesenchymal stem cells (MSC) onto osteoconductive materials to
induce a proper osteogenic differentiation and mineralized matrix regeneration represents a …

It is well acknowledged that neuroprotective effects of transplanted mesenchymal stem cells
(MSCs) in ischemic stroke are attributed to their paracrine-mediated actions or bystander …