The zebrafish has become a widely used model organism because of its fecundity, its
morphological and physiological similarity to mammals, the existence of many genomic tools …

The long-lasting success of forward genetic screens relies on the simple molecular basis of
the characterized phenotypes, which are typically caused by mutations in single genes …

Advances in vertebrate genomics have uncovered thousands of loci encoding long
noncoding RNAs (lncRNAs). While progress has been made in elucidating the regulatory …

Single nucleotide polymorphism (SNP) discovery and genotyping are essential to genetic
mapping. There remains a need for a simple, inexpensive platform that allows high-density …

How our brain is wired and subsequently generates functional output, ranging from sensing
and locomotion to emotion, decision‐making and learning and memory, remains poorly …

The zebrafish has been popular in developmental biology and genetics, but its brain
function has rarely been studied. High-throughput screening of mutation or drug-induced …

Human neuropsychiatric conditions associated with abnormally exaggerated or misdirected
fear (anxiety disorders and phobias) still represent a large unmet medical need because the …

Although zebrafish was introduced as a laboratory model organism several decades ago
and now serves as a primary model for developmental biology, there is only limited data on …

DNA sequencing by synthesis (SBS) offers an approach for potential high-throughput
sequencing applications. In this method, the ability of an incoming nucleotide to act as a …

The zebrafish (Danio rerio) has many features that make it an ideal model for the study of
developmental biology. It is small and easy to contain, it has transparent embryos, it is easy …