Screening cyclooxygenase-2 inhibitors from Allium sativum L. compounds: in silico approach

M Sadeghi, M Miroliaei, F Fateminasab… - Journal of Molecular …, 2022 - Springer
Inflammation is a natural protective response toward various simulators, including tissue
damage or pathogens. The cyclooxygenase-2 (COX-2) is a very important protein in …

Cypermethrin induces Sertoli cell apoptosis through mitochondrial pathway associated with calcium

HX Wang, R Zhang, Z Li, LS Wang, Y Yu… - Toxicology …, 2021 - academic.oup.com
Cypermethrin, one kind of pyrethroid pesticides, has been shown to act as endocrine-
disrupting chemicals (EDCs). The purpose of this study was to explore the roles of Sertoli …

Enhanced mosquitocidal efficacy of pyrethroid insecticides by nanometric emulsion preparation towards Culex pipiens larvae with biochemical and molecular …

NEM Taktak, MEI Badawy, OM Awad… - Journal of the Egyptian …, 2021 - Springer
Background The growing threat of vector-borne diseases and environmental pollution with
conventional pesticides has led to the search for nanotechnology applications to prepare …

[HTML][HTML] Downregulation of Ambra1 by altered DNA methylation exacerbates dopaminergic neuron damage in a fenpropathrin-induced Parkinson-like mouse model

S He, Q Qu, X Chen, L Zhao, Z Jiao, Z Wan… - Ecotoxicology and …, 2024 - Elsevier
Fenpropathrin (Fen), a volatile pyrethroid insecticide, is used widely for agricultural
applications and has been reported to increase the risk of Parkinson's disease (PD) …

Phytomolecules against bacterial biofilm and efflux pump: an in silico and in vitro study

R Jhanji, V Bhati, A Singh, A Kumar - Journal of biomolecular …, 2020 - Taylor & Francis
Antibiotic resistance is a global threat whose incidences are increasing day by day
worldwide. Thus, there is a need for new chemical entities (NCEs) or exploration of existing …

The effect of subacute poisoning with fenpropathrin on mice kidney function and the level of interleukin 1β and tumor necrosis factor α

M Jaremek, B Nieradko-Iwanicka - Molecular Biology Reports, 2020 - Springer
Fenpropathrin (FEN) is a pyrethroid insecticide. Mammals can be exposed to these
compounds with food and water as non-target organisms. Pyrethroids are classified into two …

Computational identification of natural product leads that inhibit mast cell chymase: An exclusive plausible treatment for Japanese encephalitis

K Kant, R Rawat, V Bhati, S Bhosale… - Journal of …, 2021 - Taylor & Francis
A recent research has identified chymase, a mast cell-specific protease as an exclusive
novel therapeutic target to prevent Japanese encephalitis virus (JEV) induced encephalitis …

Potential Therapeutic Candidates against Chlamydia pneumonia Discovered and Developed In Silico Using Core Proteomics and Molecular Docking and Simulation …

RH Kadi, KA Altammar, MM Hassan, AF Shater… - International Journal of …, 2022 - mdpi.com
Chlamydia pneumonia, a species of the family Chlamydiacea, is a leading cause of
pneumonia. Failure to eradicate C. pneumoniae can lead to chronic infection, which is why it …

Virtual screening for potential inhibitors of β (1, 3)-D-glucan synthase as drug candidates against fungal cell wall

Z Farhadi, T Farhadi… - Journal of Drug …, 2020 - Taylor & Francis
Background To enhance the outcome in patients with invasive candidiasis, initiation of an
efficient antifungal treatment in a suitable dosage is necessary. Echinocandins (eg …

Comparative toxicity of cinnamon oil, cinnamaldehyde and their nano-emulsions against Culex pipiens (L.) larvae with biochemical and docking studies

N Taktak, M Badawy, O Awad… - International Journal of …, 2022 - dergipark.org.tr
The larvicidal activity of cinnamon oil and its main component, cinnamaldehyde, was
compared with their nano-emulsions (NEs) against Culex pipiens mosquito larvae. Oil-in …