Motile and non-motile (primary) cilia are nearly ubiquitous cellular organelles. The
dysfunction of cilia causes diseases known as ciliopathies. The number of reported …

Eukaryotic cilia and flagella are evolutionarily conserved organelles that protrude from the
cell surface. The unique location and properties of cilia allow them to function in vital …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causal pathogen of
the ongoing global pandemic of coronavirus disease 2019 (COVID-19). Loss of smell and …

Primary cilia are small, antenna-like organelles that detect and transduce chemical and
mechanical cues in the extracellular environment, regulating cell behavior and, in turn …

Bardet-Biedl syndrome (BBS) is a defining ciliopathy, notable for extensive allelic and
genetic heterogeneity, almost all of which has been identified through sequencing. Recent …

BACKGROUND The precise movement of proteins and vesicles is an essential ability for all
eukaryotic cells. Nowhere is this more evident than during the remarkable transformation …

The mammalian Hedgehog (Hh) signaling pathway is required for development and for
maintenance of adult stem cells, and overactivation of the pathway can cause …

Epithelial cells lining the ducts and tubules of the kidney nephron and collecting duct have a
single non-motile cilium projecting from their surface into the lumen of the tubule. These …

The structural and functional similarity of the larval zebrafish pronephros to the human
nephron, together with the recent development of easier and more precise techniques to …

Primary cilia are organelles that are present on many different cell types, either transiently or
permanently. They play a crucial role in receiving signals from the environment and passing …