A practical approach to the management of cerebral amyloid angiopathy

MG Kozberg, V Perosa, ME Gurol… - … Journal of Stroke, 2021 - journals.sagepub.com
Cerebral amyloid angiopathy is a common small vessel disease in the elderly involving
vascular amyloid-β deposition. Cerebral amyloid angiopathy is one of the leading causes of …

Amulet or watchman device for percutaneous left atrial appendage closure: primary results of the SWISS-APERO randomized clinical trial

R Galea, F De Marco, N Meneveau, A Aminian… - Circulation, 2022 - Am Heart Assoc
Background: No study has so far compared Amulet with the new Watchman FLX in terms of
residual left atrial appendage (LAA) patency or clinical outcomes in patients undergoing …

Clinical outcomes associated with left atrial appendage occlusion versus direct oral anticoagulation in atrial fibrillation

JE Nielsen-Kudsk, K Korsholm, D Damgaard… - Cardiovascular …, 2021 - jacc.org
Objectives This study sought to investigate clinical outcomes associated with left atrial
appendage occlusion (LAAO) versus direct oral anticoagulants (DOACs) in patients with …

[HTML][HTML] Atrial fibrillation and ischemic stroke despite oral anticoagulation

R Galea, D Seiffge, L Räber - Journal of clinical medicine, 2023 - mdpi.com
Patients with atrial fibrillation (AF) experiencing ischemic stroke despite oral anticoagulation
(OAC), ie, breakthrough strokes, are not uncommon, and represent an important clinical …

[HTML][HTML] Deep Learning Framework for Real-Time Estimation of in-silico Thrombotic Risk Indices in the Left Atrial Appendage

X Morales Ferez, J Mill, KA Juhl, C Acebes… - Frontiers in …, 2021 - frontiersin.org
Patient-specific computational fluid dynamics (CFD) simulations can provide invaluable
insight into the interaction of left atrial appendage (LAA) morphology, hemodynamics, and …

[HTML][HTML] Sensitivity analysis of in silico fluid simulations to predict thrombus formation after left atrial appendage occlusion

J Mill, V Agudelo, AL Olivares, MI Pons, E Silva… - Mathematics, 2021 - mdpi.com
Atrial fibrillation (AF) is nowadays the most common human arrhythmia and it is considered
a marker of an increased risk of embolic stroke. It is known that 99% of AF-related thrombi …

Non‐Newtonian blood rheology impacts left atrial stasis in patient‐specific simulations

A Gonzalo, M García‐Villalba, L Rossini… - … journal for numerical …, 2022 - Wiley Online Library
The lack of mechanically effective contraction of the left atrium (LA) during atrial fibrillation
(AF) disturbs blood flow, increasing the risk of thrombosis and ischemic stroke. Thrombosis …

[HTML][HTML] Pulmonary vein flow split effects in patient-specific simulations of left atrial flow

E Durán, M García-Villalba, P Martínez-Legazpi… - Computers in biology …, 2023 - Elsevier
Disruptions to left atrial (LA) blood flow, such as those caused by atrial fibrillation (AF), can
lead to thrombosis in the left atrial appendage (LAA) and an increased risk of systemic …

Joint analysis of morphological parameters and in silico haemodynamics of the left atrial appendage for thrombogenic risk assessment

MI Pons, J Mill, A Fernandez-Quilez… - Journal of …, 2022 - Wiley Online Library
Background. Atrial fibrillation (AF) is considered the most common human arrhythmia. In
nonvalvular AF, around 99% of thrombi are formed in the left atrial appendage (LAA) …

[HTML][HTML] The role of the pulmonary veins on left atrial flow patterns and thrombus formation

J Mill, J Harrison, M Saiz-Vivo, C Albors, X Morales… - Scientific Reports, 2024 - nature.com
Atrial fibrillation (AF) is the most common human arrhythmia, forming thrombi mostly in the
left atrial appendage (LAA). However, the relation between LAA morphology, blood patterns …