Targeting extracellular matrix stiffness and mechanotransducers to improve cancer therapy
Y Jiang, H Zhang, J Wang, Y Liu, T Luo… - Journal of hematology & …, 2022 - Springer
Cancer microenvironment is critical for tumorigenesis and cancer progression. The
extracellular matrix (ECM) interacts with tumor and stromal cells to promote cancer cells …
extracellular matrix (ECM) interacts with tumor and stromal cells to promote cancer cells …
Role of tumor microenvironment in cancer progression and therapeutic strategy
Q Wang, X Shao, Y Zhang, M Zhu, FXC Wang… - Cancer …, 2023 - Wiley Online Library
Cancer is now considered a tumor microenvironment (TME) disease, although it was
originally thought to be a cell and gene expression disorder. Over the past 20 years …
originally thought to be a cell and gene expression disorder. Over the past 20 years …
Mesenchymal stem cell-macrophage crosstalk and maintenance of inflammatory microenvironment homeostasis
D Lu, Y Xu, Q Liu, Q Zhang - Frontiers in cell and developmental …, 2021 - frontiersin.org
Macrophages are involved in almost every aspect of biological systems and include
development, homeostasis and repair. Mesenchymal stem cells (MSCs) have good clinical …
development, homeostasis and repair. Mesenchymal stem cells (MSCs) have good clinical …
CXCL12/CXCR4 axis supports mitochondrial trafficking in tumor myeloma microenvironment
C Giallongo, I Dulcamare, D Tibullo, V Del Fabro… - Oncogenesis, 2022 - nature.com
Mesenchymal stromal cells (MSCs) within the protective microenvironment of multiple
myeloma (MM) promote tumor growth, confer chemoresistance and support metabolic needs …
myeloma (MM) promote tumor growth, confer chemoresistance and support metabolic needs …
Adipose tissue-derived mesenchymal stromal/stem cells, obesity and the tumor microenvironment of breast cancer
Simple Summary Adipose tissue is the major microenvironment of breast cancer. Adipose
tissue-derived mesenchymal stromal/stem cells (ASCs/MSCs) are key players in adipose …
tissue-derived mesenchymal stromal/stem cells (ASCs/MSCs) are key players in adipose …
Deciphering tumor niches: lessons from solid and hematological malignancies
Knowledge about the hematopoietic niche has evolved considerably in recent years, in
particular through in vitro analyzes, mouse models and the use of xenografts. Its complexity …
particular through in vitro analyzes, mouse models and the use of xenografts. Its complexity …
Exosomal miR-483-5p in bone marrow mesenchymal stem cells promotes malignant progression of multiple myeloma by targeting TIMP2
J Gu, M Wang, X Wang, J Li, H Liu, Z Lin… - Frontiers in Cell and …, 2022 - frontiersin.org
Bone marrow-derived mesenchymal stem cell (BMSC) is one crucial component of the
multiple myeloma (MM) microenvironment and supports the malignant progression of MM …
multiple myeloma (MM) microenvironment and supports the malignant progression of MM …
Metabolic pathways in immune senescence and inflammaging: Novel therapeutic strategy for chronic inflammatory lung diseases. An EAACI position paper from the …
F Roth‐Walter, IM Adcock, C Benito‐Villalvilla… - Allergy, 2024 - Wiley Online Library
The accumulation of senescent cells drives inflammaging and increases morbidity of chronic
inflammatory lung diseases. Immune responses are built upon dynamic changes in cell …
inflammatory lung diseases. Immune responses are built upon dynamic changes in cell …
Lipofilling in breast oncological surgery: a safe opportunity or risk for cancer recurrence?
F Piccotti, I Rybinska, E Scoccia, C Morasso… - International Journal of …, 2021 - mdpi.com
Lipofilling (LF) is a largely employed technique in reconstructive and esthetic breast surgery.
Over the years, it has demonstrated to be extremely useful for treatment of soft tissue defects …
Over the years, it has demonstrated to be extremely useful for treatment of soft tissue defects …
The origins and generation of cancer-associated mesenchymal stromal cells: an innovative therapeutic target for solid tumors
W Li, J Yang, P Zheng, H Li, S Zhao - Frontiers in Oncology, 2021 - frontiersin.org
Cancer-associated mesenchymal stromal cells (CA-MSCs) have been isolated from various
types of tumors and are characterized by their vigorous pro-tumorigenic functions. However …
types of tumors and are characterized by their vigorous pro-tumorigenic functions. However …