Self-training strategy based on finite element method for adaptive bioluminescence tomography reconstruction

X Zhang, X Cao, P Zhang, F Song… - … on Medical Imaging, 2022 - ieeexplore.ieee.org
Bioluminescence tomography (BLT) is a promising pre-clinical imaging technique for a wide
variety of biomedical applications, which can non-invasively reveal functional activities …

Improved intraoperative identification of close margins in oral squamous cell carcinoma resections using a dual aperture fluorescence ratio approach: first in-human …

CC Rounds, JG de Wit, J Vonk… - Journal of …, 2024 - spiedigitallibrary.org
Significance Surgical excision is the main treatment for solid tumors in oral squamous cell
carcinomas, where wide local excision (achieving a healthy tissue margin of> 5 mm around …

[HTML][HTML] Quantitative bioluminescence tomography-guided conformal irradiation for preclinical radiation research

X Xu, Z Deng, H Dehghani, I Iordachita, M Lim… - International Journal of …, 2021 - Elsevier
Purpose Widely used cone beam computed tomography (CBCT)-guided irradiators in
preclinical radiation research are limited to localize soft tissue target because of low imaging …

Self-supervised hybrid neural network to achieve quantitative bioluminescence tomography for cancer research

B Deng, Z Tong, X Xu, H Dehghani… - Biomedical Optics …, 2024 - opg.optica.org
Bioluminescence tomography (BLT) improves upon commonly-used 2D bioluminescence
imaging by reconstructing 3D distributions of bioluminescence activity within biological …

Characterization of a commercial bioluminescence tomography‐guided system for pre‐clinical radiation research

X Xu, Z Deng, D Sforza, Z Tong, YP Tseng… - Medical …, 2023 - Wiley Online Library
Abstract Background Widely used Cone‐beam computed tomography (CBCT)‐guided
irradiators have limitations in localizing soft tissue targets growing in a low‐contrast …

In vivo bioluminescence tomography-guided system for pancreatic cancer radiotherapy research

Z Deng, X Xu, H Dehghani, J Reyes… - Biomedical Optics …, 2024 - opg.optica.org
Recent development of radiotherapy (RT) has heightened the use of radiation in managing
pancreatic cancer. Thus, there is a need to investigate pancreatic cancer in a pre-clinical …

ABPO-TVSCAD: alternating Bregman proximity operators approach based on TVSCAD regularization for bioluminescence tomography

Y Chen, M Du, W Li, L Su, H Yi, F Zhao… - Physics in Medicine …, 2022 - iopscience.iop.org
Objective. Bioluminescence tomography (BLT) is a promising non-invasive optical medical
imaging technique, which can visualize and quantitatively analyze the distribution of tumor …

In vivo bioluminescence tomography center of mass-guided conformal irradiation

Z Deng, X Xu, T Garzon-Muvdi, Y Xia, E Kim… - International Journal of …, 2020 - Elsevier
Purpose The cone-beam computed tomography (CBCT)–guided small animal radiation
research platform (SARRP) has provided unique opportunities to test radiobiologic …

Design and validation of a reporter mouse to study the dynamic regulation of TFEB and TFE3 activity through in vivo imaging techniques

E Brunialti, N Rizzi, R Pinto-Costa, A Villa, A Panzeri… - Autophagy, 2024 - Taylor & Francis
ABSTRACT TFEB and TFE3 belong to the MiT/TFE family of transcription factors that bind
identical DNA responsive elements in the regulatory regions of target genes. They are …

Machine learning utilising spectral derivative data improves cellular health classification through hyperspectral infra-red spectroscopy

BOL Mellors, AM Spear, CR Howle, K Curtis… - PLoS …, 2020 - journals.plos.org
The objective differentiation of facets of cellular metabolism is important for several clinical
applications, including accurate definition of tumour boundaries and targeted wound …