Free radical properties, source and targets, antioxidant consumption and health

G Martemucci, C Costagliola, M Mariano, L D'andrea… - Oxygen, 2022 - mdpi.com
Free radicals have acquired growing importance in the fields of biology and medicine. They
are produced during many different endogenous and exogenous processes. Mitochondria …

Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Chemical Biology of H2S Signaling through Persulfidation

MR Filipovic, J Zivanovic, B Alvarez… - Chemical …, 2018 - ACS Publications
Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …

A review of hydrogen sulfide synthesis, metabolism, and measurement: is modulation of hydrogen sulfide a novel therapeutic for cancer?

X Cao, L Ding, Z Xie, Y Yang, M Whiteman… - Antioxidants & redox …, 2019 - liebertpub.com
Abstract Significance: Hydrogen sulfide (H2S) has been recognized as the third gaseous
transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous …

Near-Infrared Mitochondria-Targetable Fluorescent Probe for High-Contrast Bioimaging of H2S

S Gong, Z Zheng, X Guan, S Feng, G Feng - Analytical Chemistry, 2021 - ACS Publications
To elucidate the complex role of biological H2S and study the mitochondrial damage and
some related diseases, effective methods for visualization of H2S in mitochondria and in …

[HTML][HTML] Hydrogen sulfide: An endogenous regulator of the immune system

N Dilek, A Papapetropoulos, T Toliver-Kinsky… - Pharmacological …, 2020 - Elsevier
Hydrogen sulfide (H 2 S) is now recognized as an endogenous signaling gasotransmitter in
mammals. It is produced by mammalian cells and tissues by various enzymes …

International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors

C Szabo, A Papapetropoulos - Pharmacological reviews, 2017 - ASPET
Over the last decade, hydrogen sulfide (H2S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter

JL Wallace, R Wang - Nature reviews Drug discovery, 2015 - nature.com
Hydrogen sulfide (H2S) has become recognized as an important signalling molecule
throughout the body, contributing to many physiological and pathological processes. In …

[HTML][HTML] Intelligent polymeric hydrogen sulfide delivery systems for therapeutic applications

F Rong, T Wang, Q Zhou, H Peng, J Yang, Q Fan, P Li - Bioactive Materials, 2023 - Elsevier
Hydrogen sulfide (H 2 S) plays an important role in regulating various pathological
processes such as protecting mammalian cell from harmful injuries, promoting tissue …

Gas‐generating nanoplatforms: material chemistry, multifunctionality, and gas therapy

L Yu, P Hu, Y Chen - Advanced Materials, 2018 - Wiley Online Library
The fast advances of theranostic nanomedicine enable the rational design and construction
of diverse functional nanoplatforms for versatile biomedical applications, among which gas …