Integrative metabolomics science in Alzheimer's disease: relevance and future perspectives

S Lista, R González-Domínguez, S López-Ortiz… - Ageing Research …, 2023 - Elsevier
Alzheimer's disease (AD) is determined by various pathophysiological mechanisms starting
10–25 years before the onset of clinical symptoms. As multiple functionally interconnected …

Revolutionizing food science with mass spectrometry imaging: A comprehensive review of applications and challenges

Q Shen, S Wang, H Wang, J Liang… - … Reviews in Food …, 2024 - Wiley Online Library
Food science encounters increasing complexity and challenges, necessitating more
efficient, accurate, and sensitive analytical techniques. Mass spectrometry imaging (MSI) …

Spatial metabolomics: from a niche field towards a driver of innovation

T Alexandrov - Nature Metabolism, 2023 - nature.com
Spatial metabolomics has matured and is driving innovation in mass spectrometry,
metabolomics and spatial omics. With exciting discoveries, complementary capabilities and …

Nanospray desorption electrospray ionization (Nano-DESI) mass spectrometry imaging with high ion mobility resolution

LX Jiang, E Hernly, H Hu, RT Hilger… - Journal of the …, 2023 - ACS Publications
Untargeted separation of isomeric and isobaric species in mass spectrometry imaging (MSI)
is challenging. The combination of ion mobility spectrometry (IMS) with MSI has emerged as …

Advances in mass spectrometry for clinical analysis: Data acquisition, interpretation and information integration

H Zhang, Z Ouyang, W Zhang - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Bioinformatics has played an important role in analyzing chemical information acquired
using mass spectrometry (MS) for large numbers of biological samples. Here we review the …

[HTML][HTML] Metabolomics in drug research and development: The recent advances in technologies and applications

H Pang, Z Hu - Acta Pharmaceutica Sinica B, 2023 - Elsevier
Emerging evidence has demonstrated the vital role of metabolism in various diseases or
disorders. Metabolomics provides a comprehensive understanding of metabolism in …

A monolithic microfluidic probe for ambient mass spectrometry imaging of biological tissues

LX Jiang, M Polack, X Li, M Yang, D Belder, J Laskin - Lab on a Chip, 2023 - pubs.rsc.org
Ambient mass spectrometry imaging (MSI) is a powerful technique that allows for the
simultaneous mapping of hundreds of molecules in biological samples under atmospheric …

Deciphering Drug Targets and Actions with Single-Cell and Spatial Resolution

Z Pang, BF Cravatt, L Ye - Annual Review of Pharmacology and …, 2024 - annualreviews.org
Recent advances in chemical, molecular, and genetic approaches have provided us with an
unprecedented capacity to identify drug-target interactions across the whole proteome and …

Advances in mass spectrometry imaging for plant metabolomics—Expanding the analytical toolbox

Z Yin, W Huang, K Li, AR Fernie, S Yan - The Plant Journal, 2024 - Wiley Online Library
Mass spectrometry imaging (MSI) has become increasingly popular in plant science due to
its ability to characterize complex chemical, spatial, and temporal aspects of plant …

Noninvasive Detection of Skin Cancer by Imprint Desorption Electrospray Ionization Mass Spectrometry Imaging

Y Meng, AS Chiou, SZ Aasi, NA See, X Song… - Analytical …, 2023 - ACS Publications
We report a technique for the noninvasive detection of skin cancer by imprint desorption
electrospray ionization mass spectrometry imaging (DESI-MSI) using a transfer agent that is …