Zinc is a ubiquitous biological metal in all living organisms. The spatiotemporal zinc
dynamics in cells provide crucial cellular signaling opportunities, but also challenges for …

Nearly sixty years ago Fredrich Timm developed a histochemical technique that revealed a
rich reserve of free zinc in distinct regions of the brain. Subsequent electron microscopy …

As the second most abundant trace element in the human body, zinc nutrition is constantly a
hot topic. More than one-third population is suffering zinc deficiency, which results in various …

The Zrt‐/Irt‐like protein (ZIP) family consists of divalent metal transporters, ubiquitous in all
kingdoms of life. Since the discovery of the first ZIPs in the 1990s, the ZIP family has been …

Cadmium (Cd) pollution in cultivated land is caused by irresistible geological factors and
human activities; intense diffusion and migration have seriously affected the safety of food …

Zinc is an essential micronutrient, and its deficiency is perhaps the most prevalent and least
understood worldwide. Recent advances have expanded the understanding of zinc's unique …

The second abundant micronutrient, zinc, is attracting more and more attention for it
performs essential functions in living organisms and bears close relationships with the …

Abstract The Zrt-/Irt-like protein (ZIP) family consists of ubiquitously expressed divalent metal
transporters critically involved in maintaining systemic and cellular homeostasis of zinc, iron …

Histidine methylation has been known for many years (Searle and Westall, 1951), but only a
few proteins carrying such modifications have been studied (Webb et al., 2010; Al-Hadid et …

Nutrient transporters can be rapidly removed from the cell surface via substrate-stimulated
endocytosis as a way to control nutrient influx, but the molecular underpinnings are not well …