Highlights•New optogenetic switches open new new control modalities.•Optogenetics foster
advances in bioprocess engineering, biomedicine, and materials.•Optogenetics as interface …

Over the last twenty years, dynamic modeling of biomolecular networks has exploded in
popularity. Many of the classical tools for understanding dynamical systems are unwieldy in …

The rarity of efficient tools with spatiotemporal resolution and biocompatibility capabilities
remains a major challenge for further progress and application of signaling manipulation …

Neural progenitor cell (NPC) transplantation possesses enormous potential for the treatment
of disorders and injuries of the central nervous system, including the replacement of lost …

Biological signals are sensed by their respective receptors and are transduced and
processed by a sophisticated intracellular signaling network leading to a signal-specific …

Stimulator of interferon gene (STING) serves as a key mediator for regulating innate immune
response. Despite the dynamic process of STING activation, the role of STING clustering in …

How T lymphocytes tune their responses to different strengths of stimulation is a
fundamental question in immunology. Recent work using new optogenetic, single-cell …

Purpose Family with sequence similarity 83 (FAM83) is a newly discovered oncogene
family, and the members of which can affect the prognosis of patients with malignant tumors …

Bioluminescence-based probes have long been used to quantify and visualize biological
processes in vitro and in vivo. Over the past years, we have witnessed the trend of …

Bioluminescence-based technologies are among the most commonly used methods to
quantify and visualise physiology at the cellular and organismal levels. However, the …