[HTML][HTML] Immunotherapies of acute myeloid leukemia: Rationale, clinical evidence and perspective
Y Wu, Y Li, Y Gao, P Zhang, Q Jing, Y Zhang… - Biomedicine & …, 2024 - Elsevier
Acute myeloid leukemia (AML) is a prevalent hematological malignancy that exhibits a wide
array of molecular abnormalities. Although traditional treatment modalities such as …
array of molecular abnormalities. Although traditional treatment modalities such as …
Exploitation of In Vivo-Emulated In Vitro System in Advanced Food Science
Y Li, P Li, X Yu, X Zheng, Q Gu - Journal of Agricultural and Food …, 2023 - ACS Publications
Reasonable model construction contributes to the accuracy of experimental results. Multiple
in vivo models offer reliable choices for effective evaluation, whereas their applications are …
in vivo models offer reliable choices for effective evaluation, whereas their applications are …
Influence of probiotics on the periodontium, the oral microbiota and the immune response during orthodontic treatment in adolescent and adult patients (ProMB Trial) …
CL Seidel, RG Gerlach, M Weider, T Wölfel, V Schwarz… - BMC oral health, 2022 - Springer
Background Orthodontic treatment with fixed appliances is often necessary to correct
malocclusions in adolescence or adulthood. However, oral hygiene is complicated by …
malocclusions in adolescence or adulthood. However, oral hygiene is complicated by …
Description and optimization of a multiplex bead-based flow cytometry method (MBFCM) to characterize extracellular vesicles in serum samples from patients with …
Abstract Extracellular Vesicles (EVs) are membranous vesicles produced by all cells under
physiological and pathological conditions. In hematological malignancies, tumor-derived …
physiological and pathological conditions. In hematological malignancies, tumor-derived …
Dendritic cell-triggered immune activation goes along with provision of (leukemia-specific) integrin beta 7-expressing immune cells and improved antileukemic …
E Rackl, L Li, LK Klauer, S Ugur… - International Journal of …, 2022 - mdpi.com
Integrin beta 7 (β7), a subunit of the integrin receptor, is expressed on the surface of immune
cells and mediates cell–cell adhesions and interactions, eg, antitumor or autoimmune …
cells and mediates cell–cell adhesions and interactions, eg, antitumor or autoimmune …
Effective and successful quantification of leukemia-specific immune cells in AML patients' blood or culture, focusing on intracellular cytokine and degranulation assays
O Schutti, L Klauer, T Baudrexler, F Burkert… - International Journal of …, 2024 - mdpi.com
Novel (immune) therapies are needed to stabilize remissions or the disease in AML.
Leukemia derived dendritic cells (DCleu) can be generated ex vivo from AML patients' blasts …
Leukemia derived dendritic cells (DCleu) can be generated ex vivo from AML patients' blasts …
Volatile phases derived from serum, DC, or MLC culture supernatants to deduce a VOC-based diagnostic profiling strategy for leukemic diseases
T Baudrexler, T Boeselt, L Li, S Bohlscheid, U Boas… - Biomolecules, 2023 - mdpi.com
Volatile organic compounds (VOCs) reflect the metabolism in healthy and pathological
conditions, and can be collected easily in a noninvasive manner. They are directly …
conditions, and can be collected easily in a noninvasive manner. They are directly …
Granulocyte-Macrophage-Colony-Stimulating-Factor Combined with Prostaglandin E1 Create Dendritic Cells of Leukemic Origin from AML Patients' Whole Blood and …
M Unterfrauner, HA Rejeski, A Hartz… - International Journal of …, 2023 - mdpi.com
Although several (chemotherapeutic) protocols to treat acute myeloid leukemia (AML) are
available, high rates of relapses in successfully treated patients occur. Strategies to stabilize …
available, high rates of relapses in successfully treated patients occur. Strategies to stabilize …
Generation of Leukaemia-Derived Dendritic Cells (DCleu) to Improve Anti-Leukaemic Activity in AML: Selection of the Most Efficient Response Modifier Combinations
C Schwepcke, LK Klauer, D Deen… - International Journal of …, 2022 - mdpi.com
Dendritic cells (DC) and leukaemia derived DC (DCleu) are potent stimulators of anti-
leukaemic activity in acute myeloid leukaemia (AML) and can be generated from …
leukaemic activity in acute myeloid leukaemia (AML) and can be generated from …
Anti-Leukemic Effects Induced by Dendritic Cells of Leukemic Origin from Leukemic Blood Samples Are Comparable under Hypoxic vs. Normoxic Conditions
F Doraneh-Gard, DC Amberger, C Amend… - Cancers, 2024 - mdpi.com
Simple Summary Dendritic cells are important mediators in the activation of the innate and
adoptive immune response. The generation of DC/DCleu was comparable under …
adoptive immune response. The generation of DC/DCleu was comparable under …