Research advances defining how zinc is transported into and out of cells and organelles
have increased exponentially within the past five years. Research has progressed through …

Zinc is a key element for growth and development. In this narrative review, we focus on the
role of dietary zinc in early life (including embryo, fetus and preterm neonate), analyzing …

Copper-transporting ATPases (Cu-ATPases) ATP7A and ATP7B are evolutionarily
conserved polytopic membrane proteins with essential roles in human physiology. The Cu …

Abstract 2012 has been another year in which multiple large-scale clinical trials for
Alzheimer's disease (AD) have failed to meet their clinical endpoints. With the social and …

▪ Abstract New insights into mammalian zinc metabolism have been acquired through the
identification and characterization of zinc transporters. These proteins all have …

Copper is essential for human health and copper imbalance is a key factor in the aetiology
and pathology of several neurodegenerative diseases. The copper-transporting P-type …

In recent years, a number of mammalian zinc transporters have been identified, and
candidate genes are rapidly growing. These transporters are classified into two families: ZIP …

This article is not meant to review all of the disease states associated with zinc deficiency.
Rather, it is an introduction to the influence of the many roles of zinc in the body, with an …

Lactation is a dynamic process that has evolved to produce a complex biological fluid that
provides nutritive and nonnutritive factors to the nursing offspring. It has long been assumed …

Normal copper homeostasis is essential for human growth and development. Copper
deficiency, caused by genetic mutations, inadequate diet or surgical interventions, may lead …