Brain is a vital organ of the human body which performs very important functions such as
analysis, processing, coordination, and execution of electrical signals. For this purpose, it …

This review article attempts to present an overview of the occurrence and function of lipid
storage and secretory organelles: the lamellar bodies. Morphologically these organelles …

We have previously demonstrated that astrocytes synthesize and secrete apolipoprotein E in
situ. In the present work, primary cultures of rat brain astrocytes were used to study …

A signaling pathway involving the extracellular protein Reelin and the intracellular adaptor
protein Disabled-1 (Dab1) controls cell positioning during mammalian brain development …

Alzheimer's disease (AD) represents the main form of dementia, and is a major public health
problem. Despite intensive research efforts, current treatments have only marginal …

Recent work has demonstrated that apo E secretion and accumulation increase in the
regenerating peripheral nerve. The fact that apoE, in conjunction with apoA-I and LDL …

A 37-kDa glycoprotein has been described recently, whose synthesis is dramatically
increased after injury of the rat sciatic and optic nerves. Cells in the nerve sheath, distal to …

Observing the structure and regeneration of the myelin sheath in peripheral nerves following
injury and during repair would help in understanding the pathogenesis and treatment of …

To investigate the role of extrinsic influences on the survival and growth of axotomized
retinal ganglion cells (RGCs) in the mature mammalian CNS, both optic nerves (ONs) of …

Injuries to peripheral nerves still represent one of the most challenging surgical problems.
Severance of major nerve trunks in the upper extremity causes total or subtotal loss of …