Nicotine underlies tobacco addiction, influences tobacco use patterns, and is used as a
pharmacological aid to smoking cessation. The absorption, distribution and disposition …

The complexity of tobacco smoke leads to some confusion about the mechanisms by which
it causes lung cancer. Among the multiple components of tobacco smoke, 20 carcinogens …

Smoking has a profound impact on tumor immunity, and nicotine, which is the major
addictive component of smoke, is known to promote tumor progression despite being a non …

Smoking is associated with lung cancer and has a profound impact on tumor immunity.
Nicotine, the addictive and non-carcinogenic smoke component, influences various brain …

Introduction: Smoking is a leading cause of premature mortality and preventable morbidity.
Surveillance is most often based on self-reported data, but studies have shown that self …

Nicotine is of importance as the addictive chemical in tobacco, pharmacotherapy for
smoking cessation, a potential medication for several diseases, and a useful probe drug for …

Background: The principal objectives of this study were to examine the relationship between
cigarette smoking and periodontitis and to estimate the proportion of periodontitis in the …

A meta-analysis of worldwide studies, found by a 10-year literature follow-up and/or by
searching PubMed, was performed. Forty-two studies across 20 nations consistently …

Vitamin D is essential for bone growth (1, 2) and preservation (3), but the optimal serum 25-
hydroxy vitamin D level needed to maintain bone health is not known. Some have defined …

Background There is remarkable variation in the incidence of lung cancer among ethnic and
racial groups in the United States. Methods We investigated differences in the risk of lung …