Epigenetic mechanisms, including DNA methylation and histone post‐translational
modifications (PTMs), have been known to regulate chromatin structure and lineage‐specific …

Pulmonary arterial hypertension (PAH) is a rare disease associated with abnormally
elevated pulmonary pressures and right heart failure resulting in high morbidity and …

2020 Clinical practice guidelines for Pulmonary hypertension, including chronic thromboembolic
pulmonary hypertension | Avdeev | Russian Journal of Cardiology Russian Journal of …

Члены Рабочей группы подтвердили отсутствие финансовой поддержки/конфликта
интересов. В случае сообщения о наличии конфликта интересов, член (ы) Рабочей …

Background Data obtained in human lung tissue and preclinical models suggest that
oxidative stress and increased apoptosis signal-regulating kinase 1 (ASK1) activity might …

Children's interstitial lung disease (chILD) encompasses a wide and heterogeneous
spectrum of diseases substantially different from that of adults. Established classification …

Introduction Pulmonary arterial hypertension (PAH) is a progressive and life-threatening
disease. Approved treatment options currently primarily target abnormal cell signaling …

Pulmonary arterial hypertension (PAH) is a severe condition with a high mortality rate
despite advances in diagnostic and therapeutic strategies. In recent years, significant …

Fine control over chloride homeostasis in the lung is required to maintain membrane
excitability, transepithelial transport as well as intra-and extracellular ion and water …

Hypoxia-inducible factor (HIF) has received much attention as a potential pulmonary
hypertension (PH) treatment target because inhibition of HIF reduces the severity of …