The population genetics of pathogenic Escherichia coli

E Denamur, O Clermont, S Bonacorsi… - Nature Reviews …, 2021 - nature.com
Escherichia coli is a commensal of the vertebrate gut that is increasingly involved in various
intestinal and extra-intestinal infections as an opportunistic pathogen. Numerous pathotypes …

Genomics and pathotypes of the many faces of Escherichia coli

J Geurtsen, M de Been, E Weerdenburg… - FEMS microbiology …, 2022 - academic.oup.com
Escherichia coli is the most researched microbial organism in the world. Its varied impact on
human health, consisting of commensalism, gastrointestinal disease, or extraintestinal …

Proposal of a taxonomic nomenclature for the Bacillus cereus group which reconciles genomic definitions of bacterial species with clinical and industrial phenotypes

LM Carroll, M Wiedmann, J Kovac - MBio, 2020 - Am Soc Microbiol
The Bacillus cereus group comprises numerous closely related species, including
bioterrorism agent B. anthracis, foodborne pathogen B. cereus, and biopesticide B …

NASP: an accurate, rapid method for the identification of SNPs in WGS datasets that supports flexible input and output formats

JW Sahl, D Lemmer, J Travis, JM Schupp… - Microbial …, 2016 - microbiologyresearch.org
Whole-genome sequencing (WGS) of bacterial isolates has become standard practice in
many laboratories. Applications for WGS analysis include phylogeography and molecular …

The evolutionary conservation of Escherichia coli drug efflux pumps supports physiological functions

T Teelucksingh, LK Thompson, G Cox - Journal of bacteriology, 2020 - Am Soc Microbiol
Bacteria harness an impressive repertoire of resistance mechanisms to evade the inhibitory
action of antibiotics. One such mechanism involves efflux pump-mediated extrusion of drugs …

[HTML][HTML] Pathogenomic analyses of Shigella isolates inform factors limiting shigellosis prevention and control across LMICs

RJ Bengtsson, AJ Simpkin, CV Pulford, R Low… - Nature …, 2022 - nature.com
Shigella spp. are the leading bacterial cause of severe childhood diarrhoea in low-and
middle-income countries (LMICs), are increasingly antimicrobial resistant and have no …

[HTML][HTML] The genomic signatures of Shigella evolution, adaptation and geographical spread

HC The, DP Thanh, KE Holt, NR Thomson… - Nature Reviews …, 2016 - nature.com
Shigella spp. are some of the key pathogens responsible for the global burden of diarrhoeal
disease. These facultative intracellular bacteria belong to the family Enterobacteriaceae …

[HTML][HTML] The Intriguing Evolutionary Journey of Enteroinvasive E. coli (EIEC) toward Pathogenicity

M Pasqua, V Michelacci, ML Di Martino… - Frontiers in …, 2017 - frontiersin.org
Among the intestinal pathogenic Escherichia coli, enteroinvasive E. coli (EIEC) are a group
of intracellular pathogens able to enter epithelial cells of colon, multiplicate within them, and …

Identification of Escherichia coli and Shigella species from whole-genome sequences

MA Chattaway, U Schaefer, R Tewolde… - Journal of clinical …, 2017 - Am Soc Microbiol
Escherichia coli and Shigella species are closely related and genetically constitute the same
species. Differentiating between these two pathogens and accurately identifying the four …

[HTML][HTML] Species-wide whole genome sequencing reveals historical global spread and recent local persistence in Shigella flexneri

TR Connor, CR Barker, KS Baker, FX Weill… - elife, 2015 - elifesciences.org
Shigella flexneri is the most common cause of bacterial dysentery in low-income countries.
Despite this, S. flexneri remains largely unexplored from a genomic standpoint and is still …