Extracellular matrix (ECM) is a non-cellular three-dimensional macromolecular network
composed of collagens, proteoglycans/glycosaminoglycans, elastin, fibronectin, laminins …

Hepatocellular carcinoma (HCC) is the fifth most common cancer and the second leading
cause of cancer-related deaths worldwide. Although the prognosis of patients with HCC is …

When cancer metastasizes to bone, considerable pain and deregulated bone remodelling
occurs, greatly diminishing the possibility of cure. Metastasizing tumour cells mobilize and …

The extracellular matrix (ECM) is composed of highly variable and dynamic components that
regulate cell behavior. The protein composition and physical properties of the ECM govern …

The extracellular matrix is a structure composed of many molecules, including fibrillar (types
I, II, III, V, XI, XXIV, XXVII) and non-fibrillar collagens (mainly basement membrane collagens …

Breast tumors are characterized by an extensive desmoplastic stroma, abundantly
populated by fibroblasts. Cancer-associated fibroblasts (CAF) support tumorigenesis by …

Osteopontin (OPN) is a secreted protein present in bodily fluids and tissues. It is subject to
multiple post‐translational modifications, including phosphorylation, glycosylation …

Matricellular proteins have been classified as a family of non-structural matrix proteins
capable of modulating a variety of biological processes within the extracellular matrix (ECM) …

The signal adaptor MyD88, an essential component of TLR signaling, plays an important
role in gut-microbiome interactions. However, its contribution to colitis-associated cancer …

Obesity is a leading risk factor for cancer. However, understanding the crosstalk between
adipocytes and tumor cells in vivo, independently of dietary contributions, is a major gap in …