Among human leukocyte antigen (HLA)-associated disorders, celiac disease has an
immunopathogenesis that is particularly well understood. The condition is characterized by …

Celiac disease is a permanent intolerance to ingested gluten that results in immunologically
mediated inflammatory damage to the small-intestinal mucosa. Celiac disease is associated …

Combining HLA-DQ–gluten tetramers with mass cytometry and RNA sequencing analysis,
we find that gluten-specific CD4+ T cells in the blood and intestines of patients with celiac …

• Screening of thyroid function by measurement of thyroid stimulating hormone (TSH) and
antithyroid peroxidase antibodies is recommended at the diagnosis of diabetes (A) and …

Background & Aims Gluten ingestion leads to small intestinal mucosal injury in patients with
celiac disease, necessitating strict life-long exclusion of dietary gluten. Despite adherence to …

Coeliac disease is the manifestation of an immune hypersensitivity reaction towards gluten
and related proteins, in genetically predisposed people. Although the precise pathogenesis …

FOXP3+ regulatory T cells (Treg cells) are a specialized population of CD4+ T cells that
restrict immune activation and are essential to prevent systemic autoimmunity. In the …

BACKGROUND & AIMS:: Plasma citrulline, a nonprotein amino acid produced by
enterocytes, was suggested as a marker of remnant enterocyte mass in patients with short …

Coeliac disease is a common small bowel enteropathy arising in genetically predisposed
individuals and caused by ingestion of gluten in the diet. Great advances have been made …

Background and Aims The association between hygiene and prevalence of autoimmune
disease has been attributed in part to enteric helminth infection. A pilot study of experimental …